IMPACT OF BEDAQUILINE ON THE EFFICIENCY OF COMPREHENSIVE THERAPY OF RESPIRATORY TUBERCULOSIS
https://doi.org/10.21292/2075-1230-2018-96-6-39-43
Abstract
The objective of the study: to evaluate the possibility to enhance the clinical efficiency of treatment of pulmonary tuberculosis patients by adding bedaquiline to the fifth chemotherapy regimen.
Subjects and methods. The presented results were obtained through dynamic follow-up and treatment of 68 respiratory tuberculosis patients, treated in St. Petersburg TB Dispensary from 2014 to 2016.
Results. The clinical improvement manifested through relief of intoxication symptoms, normalization of blood count, reduction of infiltrate changes and healing of destruction. In a number of cases, relief of intoxication symptoms with reduction of bacillary excretion massiveness, infiltration and cavity sizes allowed preparing patients for the next stage of treatment – surgery.
About the Authors
M. N. Kondakova
I. I. Mechnikov Northern-Western State Medical University;
Municipal TB Dispensary
Russian Federation
Russian Federation
Professor of Phthisiopulmonology and Thoracic Surgery Department,
47, Piskarevsky Ave., St. Petersburg, 195067
V. V. Khabirov
I. I. Mechnikov Northern-Western State Medical University
Russian Federation
Russian Federation
Student of the VIth year of Training, General Medicine Department,
47, Piskarevsky Ave., St. Petersburg, 195067
V. F. Zhemkov
Municipal TB Dispensary
Russian Federation
Russian Federation
Chief Doctor,
12, Zvezdnaya St., St. Petersburg, 196158
L. R. Shpakovskaya
Municipal TB Dispensary
Russian Federation
Russian Federation
Deputy Head Doctor for Treatment,
12, Zvezdnaya St., St. Petersburg, 196158
A. V. Daynovets
Municipal TB Dispensary
Russian Federation
Russian Federation
Head of Department no. 6,
12, Zvezdnaya St., St. Petersburg, 196158
A. V. Elkin
I. I. Mechnikov Northern-Western State Medical University;
Municipal TB Dispensary
Russian Federation
Russian Federation
Head of Phthisiopulmonology and Thoracic Surgery Department,
47, Piskarevsky Ave., St. Petersburg, 195067
References
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Review
For citations:
Kondakova M.N., Khabirov V.V., Zhemkov V.F., Shpakovskaya L.R., Daynovets A.V., Elkin A.V. IMPACT OF BEDAQUILINE ON THE EFFICIENCY OF COMPREHENSIVE THERAPY OF RESPIRATORY TUBERCULOSIS. Tuberculosis and Lung Diseases. 2018;96(6):39-43. (In Russ.) https://doi.org/10.21292/2075-1230-2018-96-6-39-43
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