SPECIFIC COURSE OF KIDNEY STONE DISEASE IN CASE OF NEPHROTUBERCULOSIS
https://doi.org/10.21292/2075-1230-2018-96-7-50-54
Abstract
The objective of the study: to compare characteristics and the courses of kidney stone disease and kidney stone disease with concurrent nephrotuberculosis.
Subjects and Methods. 100 patients [55/100 ‒ women, 45/100 ‒ men (1.2/1)] with renal tuberculosis and kidney stone disease and 100 patients [67/100 ‒women, 33/100 ‒ men (2/1)] with kidney stone disease only were enrolled into the study.
Results. Сoncrements in the urinary system formed in 82% of patients after renal tuberculosis was diagnosed in them during 3-25 years, mainly against the continuous in-take of anti-tuberculosis drugs. In 18% of patients, cavernous renal tuberculosis was diagnosed only after the kidney resection due to coral calculus. 82% of patients with nephrotuberculosis developed nephrolithiasis at the age of 56-65, regardless of the time for how long they suffered from tuberculosis.
Statistically significant differences were found between the group of patients with kidney stone disease and nephrotuberculosis and the group of patients with kidney stone disease only in the following parameters: age above 60 years old, nephrolithiasis of one kidney, frequency of nephrectomies, formation of coral calculus, increase of fibrinogen level in blood serum, chronic kidney disease. All the above characteristics provide the evidence of a more severe course of kidney stone disease with concurrent nephrotuberculosis.
About the Authors
Eleonora A. Yurieva
Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Doctor of Medical Sciences, Professor, Head Researcher of General Pathology Research Laboratory.
2, Taldomskaya St., Moscow, 125412
Olga V. Konstantinova
Lopatkin Research Center of Urology and Interventional Radiology by National Medical Radiology Research Center
Russian Federation
Russian Federation
Doctor of Medical Sciences, Chief Researcher of Kidney Stone Disease Department.
51, Build. 1, the 3rd Parkovaya St., Moscow, 105425
Ekaterina S. Vozdvizhenskaya
Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Candidate of Biological Sciences, Senior Researcher of General Pathology Research Laboratory.
2, Taldomskaya St., Moscow, 125412
Maria V. Kushnareva
Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Doctor of Medical Sciences, Professor, Head Researcher of General Pathology Research Laboratory.
2, Taldomskaya St., Moscow, 125412
Sergey L. Morozov
Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Candidate of Medical Sciences, Researcher of Inherent and Acquired Renal Disorders Department.
2, Taldomskaya St., Moscow, 125412
Marina A. Podolnaya
Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Senior Researcher of Information Technology and Monitoring Department.
2, Taldomskaya St., Moscow, 125412
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Review
For citations:
Yurieva E.A., Konstantinova O.V., Vozdvizhenskaya E.S., Kushnareva M.V., Morozov S.L., Podolnaya M.A. SPECIFIC COURSE OF KIDNEY STONE DISEASE IN CASE OF NEPHROTUBERCULOSIS. Tuberculosis and Lung Diseases. 2018;96(7):50-54. (In Russ.) https://doi.org/10.21292/2075-1230-2018-96-7-50-54
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