Changes of approaches to chemotherapy in children of the tender age over 30-year period
https://doi.org/10.21292/2075-1230-2018-96-10-20-22
Abstract
The objective of the study: to analyze approaches to chemotherapy in children of the tender age over a 30-year period.
Subjects and methods. 390 children of the tender age (0-3 years old) were included in the study, they all were treated in the hospital due to tuberculosis from 1985 to 2014. Children were divided into 6 groups based on the time period (six five-year periods).
Results of the study. During different periods of time, changes in the regimens of anti-tuberculosis drugs for children in the age from 0 to 3 years old have been related to the valid regulations, making provisions for chemotherapy principles, and parameters of the drug supply to TB units. The increase in the number of drugs in treatment regimens for children of the tender age has been related to the growing frequency of drug resistant tuberculosis and it has promoted the development of a bigger number adverse reactions caused by the drugs.
About the Authors
A. R. Аroyan
Omsk State Medical University
Russian Federation
Russian Federation
Anna R. Aroyan - Post-graduate Student of Phthisiology and Phthisiosurgery Department.
12, Lenina st., Omsk, 644099.
Phone: +7 (381) 240-45-15.
E. S. Leontievа
Specialized Children Clinical Tuberculosis Hospital
Russian Federation
Russian Federation
Evgeniya S. Leontieva - Phthisiologist.
Phone: +7 (381) 246-36-45.
A. V. Mordyk
Omsk State Medical University
Russian Federation
Russian Federation
Anna V. Mordyk - Doctor of Medical Sciences, Associate Professor, Head of Phthisiology and Phthisiosurgery Department.
12, Lenina st., Omsk, 644099.
Phone: +7 (381) 240-45-15.
References
1. Vanyukov А.L., Mordyk А.V., Tsygankova E.А. Social, epidemiological and clinical characteristics of tuberculosis in children of the tender age. Sibirskoye Meditsinskoye Obozreniye, 2012, no. 1, pp. 70-73. (In Russ.)
2. Tsygankova E.А., Mordyk А.V., Turitsa А.А. Age-related manifestations of tuberculosis in children. Tuberculosis and Lung Diseases, 2014, vol. 91, no. 8, pp. 111-112. (In Russ.)
Review
For citations:
Аroyan A.R., Leontievа E.S., Mordyk A.V. Changes of approaches to chemotherapy in children of the tender age over 30-year period. Tuberculosis and Lung Diseases. 2018;96(10):20-22. (In Russ.) https://doi.org/10.21292/2075-1230-2018-96-10-20-22
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