Specific features of the immune response to tuberculosis when drug susceptible and drug resistant strains of M. tuberculosis are detected
https://doi.org/10.21292/2075-1230-2019-97-6-44-49
Abstract
The review presents literature data on the formation of the immune response to tuberculosis, features of the cellular and humoral link depending on detection of drug susceptible and drug resistant strains of M. tuberculosis. It describes the role of cytokines and genetic factors in disorders of immune reactions affecting pathomorphosis and clinical manifestations of tuberculosis.
About the Authors
L. A. Shovkun
Rostov State Medical University
Russian Federation
Russian Federation
Lyudmila A. Shovkun - Doctor of Medical Sciences, Professor, Head of Tuberculosis Department.
29, Nakhichevanskiy Lane, Rostov-on-Don, 344022.D. A. Kudlay
Immunology Research Institute by the Russian Federal Medical Biological Agency
Russian Federation
Dmitry A. Kudlay - Doctor of Medical Sciences, Leading Researcher of Laboratory for Personalized Medicine and Molecular Immunology no. 71.
Russian Federation
Dmitry A. Kudlay - Doctor of Medical Sciences, Leading Researcher of Laboratory for Personalized Medicine and Molecular Immunology no. 71.
24, Kashirskoye Highway, Moscow, 115478.
N. Yu. Nikolenko
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Nikolay Yu. Nikolenko - Researcher of Research Clinical Department.
Russian Federation
Nikolay Yu. Nikolenko - Researcher of Research Clinical Department.
10, Stromynka St., Moscow, 107014
E. D. Kampos
Rostov State Medical University
Russian Federation
Russian Federation
Elena D. Kampos - Candidate of Medical Sciences, Assistant of Tuberculosis Department.
29, Nakhichevanskiy Lane, Rostov-on-Don, 344022.
G. G. Kharseeva
Rostov State Medical University
Russian Federation
Russian Federation
Galina G. Kharseeva - Doctor of Medical Sciences, Professor, Head of Microbiology Department no. 2.
29, Nakhichevanskiy Lane, Rostov-on-Don, 344022.
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Review
For citations:
Shovkun L.A., Kudlay D.A., Nikolenko N.Yu., Kampos E.D., Kharseeva G.G. Specific features of the immune response to tuberculosis when drug susceptible and drug resistant strains of M. tuberculosis are detected. Tuberculosis and Lung Diseases. 2019;97(6):44-49. (In Russ.) https://doi.org/10.21292/2075-1230-2019-97-6-44-49
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