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Experience of using two courses of bedaquiline in the adolescent with extensive drug resistant fibrous cavernous tuberculosis

https://doi.org/10.21292/2075-1230-2019-97-7-56-60

Abstract

The article describes a clinical case demonstrating the possibility of effective and safe administration of two courses of bedaquiline within chemotherapy regimens for multiple/extensive drug resistant respiratory tuberculosis in children and adolescents. In our opinion, the treatment of patients of this age should be carried out in federal centers employing highly qualified specialists in pediatric tuberculosis.

About the Authors

L. V. Pаnovа
Central Tuberculosis Research Institute
Russian Federation

Ludmila V. Panova - Doctor of Medical Sciences, Leading Researcher of Children and Adolescents Department.

2, Yauzskaya Alleya, Moscow, 107564, Phone: +7 (499) 785-90-05



E. S. Ovsyankinа
Central Tuberculosis Research Institute
Russian Federation

Elena S. Ovsyankina - Doctor of Medical Sciences, Professor, Head of Children and Adolescents Department.

2, Yauzskaya Alleya, Moscow, 107564, Phone: +7 (499) 785-90-05



A. Yu. Khitevа
Central Tuberculosis Research Institute
Russian Federation

Antonina Yu. Khiteva - Junior Researcher of Children and Adolescents Department.

2, Yauzskaya Alleya, Moscow, 107564, Phone: +7 (499) 785-90-05



E. A. Krushinskаya
Central Tuberculosis Research Institute
Russian Federation

Ekaterina A. Volkova - Resident of Children and Adolescents Department.

2, Yauzskaya Alleya, Moscow, 107564, Phone: +7 (499) 785-90-05



References

1. Klinicheskie rekomendatsii. Tuberkulez organov dykhaniya u detey. [Clinical recommendations. Respiratory tuberculosis in children]. RSP 2016, 45 p. Available: http://roftb.ru/netcat_files/doks2017/kl_3.pdf

2. Normativnye parametry EKG u detey: Metod. rekomendatsii. [Specific parameters of EGC in children. Guidelines]. Professional Development Institute by the Russian Federal Medical Biological Agency, Moscow, MEDPRAKTIKA-M Publ., 2018, 17 p.

3. Osnovnye pokazateli po tuberkulezu po Rossiyskoy Federatsii za 2017. [Main tuberculosis rates in the Russian Federation in 2017]. FGBU TSNIIOIZ Minzdrava Rossii Publ., Available:http://mednet.ru/images/stories/tb2017.pdf

4. New and Repurposed Drugs for Pediatric Multidrug-Resistant Tuberculosis Practice-based Recommendations. Am. J. Respir. Crit. Care Med., vol. 195, iss. 10, pp. 1300-1310, May 15, 2017 CDOI:10.1164/rccm.201606-1227CI.

5. WHO treatment guidelines for multidrug- and rifampicin-resistant tuberculosis 2018 update Prefinal text. www.who.int/tb/publications/2018/WHO.2018.MDR-TB.Rx.Guidelines.prefinal.text.pdf


Review

For citations:


Pаnovа L.V., Ovsyankinа E.S., Khitevа A.Yu., Krushinskаya E.A. Experience of using two courses of bedaquiline in the adolescent with extensive drug resistant fibrous cavernous tuberculosis. Tuberculosis and Lung Diseases. 2019;97(7):56-60. (In Russ.) https://doi.org/10.21292/2075-1230-2019-97-7-56-60

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)