The experience of surgical treatment of tuberculosis and non-specific arthritis with two-stage arthroplasty using articulating cement spacers saturated with antibiotics
https://doi.org/10.21292/2075-1230-2019-97-11-25-32
Abstract
The objective: to analyze the results of surgical treatment of tuberculosis and non-specific arthritis of large joints of extremities by two-stage endoprosthesis replacement using cement articulating spacers saturated with antibiotics.
Subjects and methods. The prospective single-center cohort trial included 36 clinical cases in 35 patients with purulent destructive arthritis of the hip, knee, and shoulder joints, who underwent two-stage surgery from 2010 to 2018. This method implied using cement articulating spacers at the first stage of surgery followed by replacement with a prosthetic implant. Joint tuberculosis was diagnosed in 7 (20.0%) patients, all other cases were non-specific arthritis.
Results. In all 36 cases, patients underwent a full cycle of two-stage endoprosthesis replacement of joints affected by tuberculosis or non-specific infection resulting in pronounced destructive changes. In 33 clinical cases of the patients (91.67%), a positive outcome was observed with restoration of joint and extremity function in general with persistent eradication of the infection. An unfavorable outcome was obtained in 3 patients due to development of periprosthetic infection and loosening of the implant, 2 of them had tuberculous arthritis.
About the Authors
V. S. Zubikov
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
Russian Federation
Russian Federation
Vladimir S. Zubikov - Doctor of Medical Sciences, Professor, Leading Researcher
of Extrapulmonary Tuberculosis Research Department
4, Dostoevsky St., Moscow, 127473
E. O. Peretsmanas
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
Russian Federation
Russian Federation
Evgeniy O. Peretsmanas - Doctor of Medical Sciences, Head of Extrapulmonary
Tuberculosis Research Department, Honored Doctor of Russia
4, Dostoevsky St., Moscow, 127473
I. A. Gerasimov
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
Russian Federation
Russian Federation
Ilya A. Gerasimov - Trauma Orthopaedist of Extrapulmonary Tuberculosis
Department
4, Dostoevsky St., Moscow, 127473
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Review
For citations:
Zubikov V.S., Peretsmanas E.O., Gerasimov I.A. The experience of surgical treatment of tuberculosis and non-specific arthritis with two-stage arthroplasty using articulating cement spacers saturated with antibiotics. Tuberculosis and Lung Diseases. 2019;97(11):25-32. (In Russ.) https://doi.org/10.21292/2075-1230-2019-97-11-25-32
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