Feasibility of the concept for respiratory tuberculosis chemotherapy in children and adolescents
https://doi.org/10.21292/2075-1230-2019-97-11-41-45
Abstract
The article presents the review of publications devoted to personalized tuberculosis chemotherapy in children and adolescents with consideration of the specific course of the disease with the relevance to age. It is possible to reduce the duration of chemotherapy and the number of anti-tuberculosis drugs within the regimen. At the same time, the major criteria include results of microbiological tests of diagnostic specimens of the patient’s and/or index case and drug susceptibility tests in full both by express and traditional microbiological methods, microbiological and radiological monitoring, primarily in the intensive phase of chemotherapy. Generally, this personalized approach can assure high treatment efficacy.
About the Authors
E. S. Ovsyankina
Central Tuberculosis Research Institute
Russian Federation
Russian Federation
Elena S. Ovsyankina - Doctor of Medical Sciences, Professor, Head of Children and Adolescents Department
2, Yauzskaya Alleya, Moscow, 107564
M. F. Gubkina
Central Tuberculosis Research Institute
Russian Federation
Russian Federation
Marina F. Gubkina - Doctor of Medical Sciences, Chief Researcher of Children and Adolescents Department
2, Yauzskaya Alleya, Moscow, 107564
L. V. Panova
Central Tuberculosis Research Institute
Russian Federation
Russian Federation
Ludmila V. Panova - Doctor of Medical Sciences, Leading Researcher of Children and Adolescents Department
2, Yauzskaya Alleya, Moscow, 107564
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For citations:
Ovsyankina E.S., Gubkina M.F., Panova L.V. Feasibility of the concept for respiratory tuberculosis chemotherapy in children and adolescents. Tuberculosis and Lung Diseases. 2019;97(11):41-45. (In Russ.) https://doi.org/10.21292/2075-1230-2019-97-11-41-45
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