Specific characteristics of epidemiology and clinical manifestations of tuberculosis spondylitis in Ulyanovsk Region
https://doi.org/10.21292/2075-1230-2020-98-2-30-34
Abstract
The objective: to study specific characteristics of epidemiology and clinical manifestations of tuberculosis spondylitis in Ulyanovsk Region.
Subjects and methods: Annual reports of the regional TB dispensary and medical records of all 160 tuberculosis spondylitis patients detected 2009 to 2018 were reviewed. Radiation, laboratory, bacteriological, immunological, molecular genetic, and morphological diagnostic methods were used. Reliability was assessed using the software of Statistica 8.0: in the frequency of events according to χ2, and in the median values according to the discrepancy test.
Results. It was found out that the incidence of tuberculosis spondylitis and its share in the structure of newly detected extrapulmonary forms had increased; tuberculosis spondylitis had specific symptoms such as the severe course with destruction of the vertebral bodies, leaky abscesses, neurological disorders with moderate intoxication; the main pathogenetic mechanism was the activation of foci of the primary period of tuberculosis infection in vertebral bodies, which was facilitated by HIV infection, chronic viral hepatitis, alcohol, and drug addiction.
About the Authors
L. N. Savonenkova
Ulyanovsk State University
Russian Federation
Russian Federation
Professor of Faculty Therapy Department (with the Training Course in Phthisiology)
42, Lva Tolstogo St., Ulyanovsk, 432017
Phone: +7 (8422) 41-20-88, +7 (8422) 41-15-92
V. I. Ruzov
Ulyanovsk State University
Russian Federation
Russian Federation
Head of Faculty Therapy Department (with the Training Course in Phthisiology)
42, Lva Tolstogo St., Ulyanovsk, 432017
Phone: +7 (8422) 41-20-88, +7 (8422) 41-15-92
S. V. Аnisimova
Ulyanovsk State University
Russian Federation
Resident of Faculty Therapy Department (with the Training Course in Phthisiology)
Russian Federation
Resident of Faculty Therapy Department (with the Training Course in Phthisiology)
42, Lva Tolstogo St., Ulyanovsk, 432017
Phone: +7 (8422) 41-20-88, +7 (8422) 41-15-92
T. S. Vasilieva
Ulyanovsk State University
Russian Federation
Russian Federation
Resident of Faculty Therapy Department (with the Training Course in Phthisiology)
42, Lva Tolstogo St., Ulyanovsk, 432017
Phone: +7 (8422) 41-20-88, +7 (8422) 41-15-92
V. S. Dunaev
Ulyanovsk State University
Russian Federation
Russian Federation
Resident of Faculty Therapy Department (with the Training Course in Phthisiology)
42, Lva Tolstogo St., Ulyanovsk, 432017
Phone: +7 (8422) 41-20-88, +7 (8422) 41-15-92
D. V. Kolchin
Ulyanovsk State University
Russian Federation
Russian Federation
Post Graduate Student of Faculty Therapy Department (with the Training Course in Phthisiology)
42, Lva Tolstogo St., Ulyanovsk, 432017
Phone: +7 (8422) 41-20-88, +7 (8422) 41-15-92
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Review
For citations:
Savonenkova L.N., Ruzov V.I., Аnisimova S.V., Vasilieva T.S., Dunaev V.S., Kolchin D.V. Specific characteristics of epidemiology and clinical manifestations of tuberculosis spondylitis in Ulyanovsk Region. Tuberculosis and Lung Diseases. 2020;98(2):30-34. (In Russ.) https://doi.org/10.21292/2075-1230-2020-98-2-30-34
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