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Clinical signs of tuberculosis relapses in HIV patients

https://doi.org/10.21292/2075-1230-2020-98-6-32-35

Abstract

The objective: to study clinical manifestations of tuberculosis relapses and their treatment outcomes in patients with HIV infection.

Subjects and Methods. 132 medical records of patients with tuberculosis relapses were analyzed; 69 of them were HIV-positive and 63 were HIV-negative. All of them were admitted to Irkutsk Regional Clinical Tuberculosis Hospital from 2016 to 2019, and then continued treatment of tuberculosis on the out-patient basis. Treatment efficacy was assessed in February 2020.

Results. More severe clinical forms of tuberculosis relapses were typical of HIV patients including generalized forms affecting the central nervous system. Therefore, among these patients, the mortality rate is significantly higher (24.6%) than in tuberculosis relapses with no concurrent HIV infection (6.3%), p ≤ 0.05.

About the Authors

E. Yu. Zorkаltsevа
Irkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuing Professional Education
Russian Federation

Elena Yu. Zorkaltseva, Doctor of Medical Sciences, Professor, Head of Phthisiology and Infectious Diseases Department.

100, Yubileyny Mikroraion St., Irkutsk, 664049.



Yu. O. Egorovа
Irkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuing Professional Education
Russian Federation

Yulia O. Egorova, Post Graduate Student of Tuberculosis and Infectious Diseases Department.

100, Yubileyny Mikroraion St., Irkutsk, 664049.



References

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For citations:


Zorkаltsevа E.Yu., Egorovа Yu.O. Clinical signs of tuberculosis relapses in HIV patients. Tuberculosis and Lung Diseases. 2020;98(6):32-35. (In Russ.) https://doi.org/10.21292/2075-1230-2020-98-6-32-35

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)