MDR tuberculosis and HIV infection in the North-Western Federal District
https://doi.org/10.21292/2075-1230-2021-99-1-27-32
Abstract
The objective of the study: to study changes in MDR tuberculosis incidence and prevalence among patients with HIV infection in the North-Western Federal District and its regions in 2007-2018.
Subjects and methods. The data from FSN Form No. 61 on Information on HIV Infected Patients Contingents for 2007-2018, materials of Federal Research Institute for Health Organization and Informatics by the Russian Ministry of Health, information from tables additionally developed by the authors were used. Epidemiological and statistical methods were applied; the differences between the variables were established by the Fisher coefficient based on the Statistica software.
Results. The increase in the incidence of TB/HIV co-infection is the highest in regions with the low cumulation of HIV infection: Arkhangelsk, Pskov Regions and the Komi Republic. In 2018, MDR TB among HIV patients with HIV was the most prevalent in Leningrad Region (37.7%), the Komi Republic (32.2%) and Novgorod Region (29.3%), while in the Republic of Karelia, there was not a single case of MDR TB detected among HIV patients, in Pskov Region - 2.4% of cases. The efficacy of tuberculosis chemotherapy by regimens IV-V among the MDR TB/HIV cohort was statistically significantly lower than that of the entire MDR TB cohort: 41.4% versus 61.5% (p < 0.04).
About the Authors
Z. M. Zagdyn
St. Petersburg Research Institute of Phthisiopulmonology
Russian Federation
Russian Federation
Zinaida M. Zagdyn - Candidate of Medical Sciences, Senior Researcher of Epidemiology and Statistics Department.
2/4, Ligovsky Ave., St. Petersburg, 191036Y. Zhao
St. Petersburg Research Institute of Phthisiopulmonology; University of Michigan
United States
United States
Yimeng Zhao - Student of Research Program of Statistics Reporting Department, Bachelor of Science in Chemistry, the University of Michigan.
2/4, Ligovsky Ave., St. Petersburg, 191036
E. G. Sokolovich
St. Petersburg Research Institute of Phthisiopulmonology; St. Petersburg University
Russian Federation
Russian Federation
Evgeniy G. Sokolovich - Doctor of Medical Sciences, Professor, Deputy Director for Research.
2/4, Ligovsky Ave., St. Petersburg, 191036
P. K. Yablonskiy
St. Petersburg Research Institute of Phthisiopulmonology; St. Petersburg University
Russian Federation
Russian Federation
Petr K. Yablonskiy - Doctor of Medical Sciences, Professor, Director.
2/4, Ligovsky Ave., St. Petersburg, 191036
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Review
For citations:
Zagdyn Z.M., Zhao Y., Sokolovich E.G., Yablonskiy P.K. MDR tuberculosis and HIV infection in the North-Western Federal District. Tuberculosis and Lung Diseases. 2021;99(1):27-32. (In Russ.) https://doi.org/10.21292/2075-1230-2021-99-1-27-32
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