Characteristics of Complications after Pulmonary Tuberculosis Surgery in HIV-Infected Patients with Different CD4+ Levels and Viral Load
https://doi.org/10.21292/2075-1230-2021-99-6-7-13
Abstract
The objective: to study postoperative complications in pulmonary tuberculosis HIV positive patients with the relevance to CD4+ count and viral load before surgery.
Subjects and methods. The results of planned lung resections of various extent for tuberculosis in 139 HIV positive patients were analyzed.
Results. There was no statistically significant correlation between baseline CD4+ count and viral load and the development of postoperative complications in the investigated cases.
About the Authors
D. V. АlkazRussian Federation
Denis V. Аlkaz – Surgical Department no. 2.
41, Kirochnaya St., St. Petersburg, 191015
T. S. Basek
Russian Federation
Taufik S. Basek – Candidate of Medical Sciences, Assistant of Phthisiopulmonology and Thoracic Surgery Department.
41, Kirochnaya St., St. Petersburg, 191015
A. M. Panteleev
Russian Federation
Aleksandr M. Panteleev – Doctor of Medical Sciences, Head Physician.
12, Zvezdnaya St., St. Petersburg, 196142
K. V. Vladimirov
Russian Federation
Kirill B. Vladimirov – Candidate of Medical Sciences, Associate Professor of Phthisiopulmonology and Thoracic Surgery Department.
41, Kirochnaya St., St. Petersburg, 191015
A. V. Elkin
Russian Federation
Aleksey V. Elkin – Doctor of Medical Sciences, Professor, Head of Phthisiopulmonology and Thoracic Surgery Department.
41, Kirochnaya St., St. Petersburg, 191015
References
1. Аlkaz D.V., Basek T.S., Dzhamshedov D.Sh., Elkin А.V. The impact of medical and social factors on outcomes of surgical treatment of pulmonary tuberculosis in HIV positive patients. Tuberculosis and Lung Diseases, 2018, vol. 96, no. 2, pp. 11-15. (In Russ.) doi: 10.21292/2075-1230-2018-96-2-11-15.
2. Аlkaz D.V., Basek T.S., Pashina Yu.I., Dzhamshedov D.Sh., Panteleev А.M., Elkin А.V. Frequency and nature of complications after lung resections for tuberculosis in HIV-infected patients. Vestnik Khirurgii im. I. I. Grekova, 2018, vol. 177, no. 5, pp. 74-79. (In Russ.) doi: 10.24884/0042-4625-2018-177-5-74-79.
3. Barinova А.N., Plavinskiy S.L., Vinogradova N.Kh. The use of simultaneous data to assess the intensity of infection of intravenous drug users with HIV infection and viral hepatitis C - there is no constant risk. Vestnik Severo-Zapadnogo Gosudarstvennogo Meditsinskogo Universiteta Im. I. I. Mechnikova, 2015, vol. 7, no. 1, pp. 78-87. (In Russ.)
4. Gordon А.I., Viktorova I.B., Dolgikh S.А. The experience of drug resistant tuberculosis treatment in HIV positive patients. Tuberculosis and Lung Diseases, 2014, no. 12, pp. 66-68. (In Russ.)
5. Кaminskiy G.D., Kudlay D.А., Panova А.E., Parolina L.E., Peregudova А.B., Pshenichnaya N.Yu., Samoylova А.G., Testov V.V., Tinkova V.V. Taktika vracha pri vyyavlenii, diagnostike i profilaktike sochetannoy infektsii VICH i tuberkulez: prakticheskoe rukovodstvo. [Tactics of the physician in the detection, diagnosis and prevention of TB/HIV coinfection. Practical guide]. I.A. Vasilyeva, eds., Moscow, 2020, 152 p.
6. Mamaev А.N., Kudlay D.А. Statisticheskiye metody v meditsine. [Statistical methods in medicine]. Moscow, Prakticheskaya Meditsina Publ., 2021, 136 p. ISBN 978-5-98811-635-6.
7. Mordyk А.V., Ivanova O.G., Sitnikova S.V. Tuberculosis with concurrent HIV-infection: causes of treatment failures. Omskiy Nauchny Vestnik, 2015, no. 2 (144), pp. 23-26. (In Russ.)
8. Edict no. 166 by the Russian Ministry of Health and Social Development as of March 17, 2006 On Approval of Instructions for Completing Annual Form of Federal State Statistical Surveillance no. 61 on Contingents of Patients with HIV Infection. (In Russ.) Available: https://www.webapteka.ru/phdocs/doc11200.html (Accessed 21.03.2018).
9. Salina T.Yu., Morozova T.I. Clinical manifestations and treatment efficiency of those suffering from TB/HIV co-infection and hepatitis. Tuberculosis and Lung Diseases, 2017, vol. 95, no. 9, pp. 25-29. (In Russ.) doi: 10.21292/2075-1230-2017-95-9-25-29.
10. Sinitsyn M.V., Virskiy N.Yu., Tityukhina M.V., Barskiy B.G., Аbu Аrkub T.I., Kalinina M.V. Surgical treatment of tuberculosis in HIV patients. Tuberculosis and Lung Diseases, 2018, vol. 96, no. 7, pp. 18-24. (In Russ.) doi: 10.21292/2075-1230-2018-96-7-18-24.
11. Federalnye klinicheskie rekomendatsii po diagnostike i lecheniyu tuberkuleza u bolnykh VICH-infektsiey ot 2016g. [Federal clinical guidelines on diagnostics and treatment of tuberculous in HIV patients as of 2016]. Available: http://roftb.ru/netcat_files/doks2016/rec2016.pdf (Accessed 21.05.2020).
12. Federal Scientific Methodical Center for AIDS Prevention and Control, Central Research Institute of Epidemiology, Federal Service on Customers’ Rights Protection and Human Well-being Surveillance. (In Russ.) Available: http://www.hivrussia.info/wp-content/uploads/2020/02/VICH-infektsiya-v-Rossijskoj-Federatsii-na-31.12.2019.pdf (Accessed 21.05.2020).
13. Shilova M.V. Tuberculosis in Russia. Tuberculosis mortality. Med. Alfavit, 2018, vol. 1, no. 10 (347), pp. 42-50. (In Russ.)
14. 1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults. Available: https://www.cdc.gov/mmwr/preview/mmwrhtml/00018871.htm (Accessed 22.05.2020).
15. Alexander G.R. A retrospective review comparing the treatment outcomes of emergency lung resection for massive haemoptysis with and without preoperative bronchial artery embolization. Eur. J. Cardiothorac. Surg., 2014, no. 45, pp. 251-255. doi: 10.1093/ejcts/ezt336.
16. Alexander G.R., Biccard B. A retrospective review comparing treatment outcomes of adjuvant lung resection for drug-resistant tuberculosis in patients with and without human immunodeficiency virus co-infection. Eur. J. Cardiothorac. Surg., 2016, no. 49, pp. 823-828. doi: 10.1093/ejcts/ezv228.
17. Jeremiah L., Jessics G., Deneve: CD4 count is predictive of outcome in HIV-positive patients undergoing abdominal operations. Am. J. Surg., 2010, no. 200 (6), pp. 694-700. doi: 10.1016/j.amjsurg.2010.07.030.
18. Liu B., Zhang L., Guo R., Su J., Li L., Si Y. Anti-infective treatment in HIV-infected patients during perioperative period. AIDS Research and Therapy, 2012, no. 9, pp. 36. doi: 10.1186/1742-6405-9-36.
19. Madansein R., Parida S., Padayatchi N., Singh N., Master I., Naidu K., Zumla A., Maeurer M. Surgical treatment of complications of pulmonary tuberculosis, including drug-resistant tuberculosis. Intern. J. Infect. Dis., 2015, no. 32, pp. 61-67. doi: 10.1016/j.ijid.2015.01.019.
Review
For citations:
Аlkaz D.V., Basek T.S., Panteleev A.M., Vladimirov K.V., Elkin A.V. Characteristics of Complications after Pulmonary Tuberculosis Surgery in HIV-Infected Patients with Different CD4+ Levels and Viral Load. Tuberculosis and Lung Diseases. 2021;99(6):7-13. (In Russ.) https://doi.org/10.21292/2075-1230-2021-99-6-7-13