Endoscopic Diagnosis of Bronchial Tuberculosis in Pulmonary Tuberculosis Patients with Different HIV Status
https://doi.org/10.21292/2075-1230-2022-100-7-28-33
Abstract
The objective: to compare the effectiveness of endoscopic diagnosis of bronchial tuberculosis in pulmonary tuberculosis patients with different HIV status.
Subjects and Methods. The data obtained during tracheobronchoscopy in 371 respiratory tuberculosis patients from 2018 to 2020 were retrospectively studied. The indication for bronchoscopy was the presence of clinical and radiological symptoms characteristic of bronchial tuberculosis in a pulmonary tuberculosis patient. All patients were divided into two groups: HIV+ and HIV-.
Results. In pulmonary tuberculosis patients with clinical and radiographic findings characteristic of bronchial tuberculosis, the frequency of endoscopic confirmation of bronchial tuberculosis in HIV+ Group was 57/71 (80.3%), in HIV- Group – 138/300 (46.0%), p < 0.01; χ2 = 27.06.
Most often, in HIV-positive patients, the infiltrative form of bronchus tuberculosis was detected – 27 (47.4%) patients, and the fistulous form – 23 (40.4%) patients, bronchial lesions in HIV negative tuberculosis patients were mainly infiltrative – 94 (68.1%) or ulcerative – 24 (17.4%).
The frequency of microbiological detection of the causative agent of tuberculosis increased when bronchobiopsy was performed versus sputum microscopy, especially in HIV negative tuberculosis patients (from 39.9 to 91.3%), and among HIV positive patients from 15.7 to 47.4%.
About the Authors
M. V. Sinitsyn
Moscow Research and Clinical Center for Tuberculosis Control
Russian Federation
Russian Federation
Mikhail V. Sinitsyn, Doctor of Medical Sciences, Deputy Director
10, Stromynka St., Moscow, 107014
Phone: +7 (499) 268-28-10
S. V. Bykov
Moscow Research and Clinical Center for Tuberculosis Control
Russian Federation
Russian Federation
Sergey V. Bykov, Endoscopist of Endoscopy Department of Clinic no. 2
10, Stromynka St., Moscow, 107014
Phone: +7 (499) 268-28-10
M. N. Reshetnikov
Moscow Research and Clinical Center for Tuberculosis Control
Russian Federation
Russian Federation
Mikhail N. Reshetnikov, Candidate of Medical Sciences, Surgeon of Tuberculosis Surgery Department of Clinic no. 2
10, Stromynka St., Moscow, 107014
Phone: +7 (499) 268-28-10
I. S. Aralova
Moscow Research and Clinical Center for Tuberculosis Control
Russian Federation
Russian Federation
Irina S. Aralova, Endoscopist of Endoscopy Department of Clinic no. 2
10, Stromynka St., Moscow, 107014
Phone: +7 (499) 268-28-10
A. G. Antipov
Moscow Research and Clinical Center for Tuberculosis Control
Russian Federation
Russian Federation
Aleksander G. Antipov, Endoscopist of Endoscopy Department of Clinic no. 2
10, Stromynka St., Moscow, 107014
Phone: +7 (499) 268-28-10
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For citations:
Sinitsyn M.V., Bykov S.V., Reshetnikov M.N., Aralova I.S., Antipov A.G. Endoscopic Diagnosis of Bronchial Tuberculosis in Pulmonary Tuberculosis Patients with Different HIV Status. Tuberculosis and Lung Diseases. 2022;100(7):28-33. (In Russ.) https://doi.org/10.21292/2075-1230-2022-100-7-28-33
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