Comparative Analysis of Results of Transbronchial Needle Aspiration Biopsy of Mediastinal Lymph Nodes with Flexible and Rigid Tracheobronchoscopy for Verification of Mediastinal Lymphadenopathies
https://doi.org/10.58838/2075-1230-2023-101-3-15-20
Abstract
The objective: to analyze results of TBNA for diagnosis of mediastinal lymphadenopathy performed with flexible and rigid tracheobronchoscopy with needles of different diameters.
Subjects and Methods. We analyzed data of 194 patients who underwent TBNA with fibrobronchoscopy (Group 1) or rigid bronchoscopy (Group 2) for mediastinal lymphadenopathy of uncertain etiology.
Results. The overall diagnostic efficacy of the biopsy was 90,7%, while in case of tumors, the sensitivity was 89,5% and specificity was 97,5%, in case of respiratory sarcoidosis, they were 92,5% and 85,9%, respectively. Better diagnostic efficacy rates were observed in Group 1 (flexible bronchoscopy with 19G puncture needles) versus Group 2 (rigid bronchoscopy with 16G puncture needles) which may be due to the small number of biopsies in Group 2.
About the Authors
N. A. Samorodov
TB Dispensary, Ministry of Health of the Kabardino-Balkarian Republic
Russian Federation
Russian Federation
Nikolay A. Samorodov, Head of Diagnostic Department
13, Naloeva St., Nalchik, the Kabardino-Balkarian Republic, 360032
Phone: +7 (928) 700-49-57
I. A. Miziev
Kabardino-Balkarian State University Named After H. M. Berbekov
Russian Federation
Russian Federation
Ismail A. Miziev, Doctor of Medical Sciences, Dean of Medicine Faculty
173, Chernyshevskogo St., Nalchik, the Kabardino-Balkarian Republic, 360000
Phone: +7 (928) 716-53-56
Zh. Kh. Sabanchieva
Kabardino-Balkarian State University Named After H. M. Berbekov
Russian Federation
Russian Federation
Zhaneta Kh. Sabanchieva, Doctor of Medical Sciences, Professor of Department of Public Health and Healthcare and Preventive Medicine
173, Chernyshevskogo St., Nalchik, the Kabardino-Balkarian Republic, 360000
Phone: +7 (965) 497-90-30
L. V. Elgarova
Kabardino-Balkarian State University Named After H. M. Berbekov
Russian Federation
Russian Federation
Lilya V. Elgarova, Doctor of Medical Sciences, Professor, Head of Propedeutics of Internal Diseases Department
173, Chernyshevskogo St., Nalchik, the Kabardino-Balkarian Republic, 360000
Phone: +7 (928) 708-27-62
References
1. Anufriev A. V., Nevdashenko A. A., Shebushev N. G. Videothoracoscopy in the diagnosis of disseminated processes in the lungs and mediastinal adenopathy. Tezisy dokladov po torakoskopicheskoy khirurgii. [Abst. Book for thoracoscopic surgery]. St. Petersburg, 1997, pp. 6–8. (In Russ.)
2. Vishnevsky A. A., Adamyan A. A. Khirurgiya sredosteniya. [Mediastinal surgery]. Moscow, Meditsina Publ., 1977, 399 p.
3. Klimenko V. N., Barchuk L. S., Lemekhov V. G., Scherbakov A. M. Videothoracoscopy in the diagnosis and treatment of neoplasms of the lung, mediastinum and pleura. Voprosy Onkologii, 2002, no. 3, pp. 371–376. (In Russ.)
4. Kudryashov G. G., Vasiliev I. V., Zaytsev I. A., Novitskaya T. A., Zhuravlev V Yu., Archakova L. I., Avetisyan A. O., Kozak A. R., Yablonskiy P. K. The use of transbronchial aspiration of mediastinal lymph nodes under ultrasound control in the differential diagnosis of tuberculous lymphadenitis in patients with mediastinal lymphadenopathy. Meditsinskiy Alyans, 2017, no. 2, pp. 35–42. (In Russ.)
5. Aggarwal R., Rao S., Chopra P., et al. Morphological spectrum of mediastinal lesions with special emphasis on evaluation of needle biopsy: An experience from a tertiary care hospital // Indian J. Med. Res. – 2016. – Vol. 144, № 4. – P. 544–551.
6. Gu P., Zhao Y. Z., Jiang L. Y., Zhang W., Xin Y., Han B. H. Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a systematic review and meta-analysis // Eur. J. Cancer. – 2009. – № 45. – P. 1389–96.
7. Nakajima T., Yasufuku K., Saegusa F., Fujiwara T., Sakairi Y., Hiroshima K., et al. Rapid on-site cytologic evaluation during endobronchial ultrasound-guided transbronchial needle aspiration for nodal staging in patients with lung cancer // Ann. Thorac. Surg. – 2012. – № 37. – P. 316–26.
8. Pasiyeshvili L. M. Lymphadenopathy: definytion and diagnosis // East European Magazine of Internal and Family Medicine. – 2016. – № 1. – P. 46–56.
9. Sayar A., Citak N., Metin M., Turna A., Pekçolaklar A., Kök A., et al. Comparison of video-assisted mediastinoscopy and video-assisted mediastinoscopic lymphadenectomy for lung cancer // Gen Thorac Cardiovasc Surg. – 2011. – № 59. – P. 793–798.
10. Tomlinson G. S. et al. Transcriptional Profiling of Endobronchial 10. Tomlinson G. S. et al. Transcriptional Profiling of Endobronchial Ultrasound-Guided Lymph Node Samples Aids Diagnosis of Mediastinal Ultrasound-Guided Lymph Node Samples Aids Diagnosis of Mediastinal Lymphadenopathy // CHEST Journal. – 2016. – Vol. 149. – № 2. – P. 535–544. Lymphadenopathy. CHEST Journal, 2016, vol. 149, no. 2, pp. 535–544.
11. Vilmann P., Larsen S. S., Krasnik M. EUS-guided FNA for mediastinal tumors 11. Vilmann P., Larsen S. S., Krasnik M. EUS-guided FNA for mediastinal tumors (lung cancer and lymph nodes) // Digestive Endosc. — 2004. — Vol. 16, suppl. 2. – P. 185–192
Review
For citations:
Samorodov N.A., Miziev I.A., Sabanchieva Zh.Kh., Elgarova L.V. Comparative Analysis of Results of Transbronchial Needle Aspiration Biopsy of Mediastinal Lymph Nodes with Flexible and Rigid Tracheobronchoscopy for Verification of Mediastinal Lymphadenopathies. Tuberculosis and Lung Diseases. 2023;101(3):15-20. (In Russ.) https://doi.org/10.58838/2075-1230-2023-101-3-15-20
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