Ways to Enhance the Diagnosis of Pulmonary Sarcoidosis (Literature Review)
Yu. S. Zinchenko,
V. O. Polyakova,
A. N. Muraviev,
I. R. Tubeeva,
S. V. Starevskaya,
P. K. Yablonskiy https://doi.org/10.58838/2075-1230-2025-103-2-102-110
Abstract
The article analyzes 50 publications devoted to diagnostic approaches to detection of sarcoidosis. It highlights that currently diagnosis of this disease is not standardized and thus errors are highly possible to occur. Improved approaches address all aspects of diagnosis, from the distinction of highly specific clinical and radiologic signs of the disease to the choice of lung biopsy method. The use of sarcoidosis biomarkers such as angiotensin-converting enzyme, chitotriosidase, and serum amyloid A is most promising. The possibility of their combination and association with clinical signs of the disease are being studied, and to discover new biomarkers, full-genome studies are being in progress.
About the Authors
Yu. S. Zinchenko
St. Petersburg Research Institute of Phthisiopulmonology, Russian Ministry of Health
Russian Federation
Russian Federation
Yulia S. Zinchenko - Candidate of Medical Sciences, Senior Researcher, Head of Research Laboratory of Non-Specific Lung Diseases
2-4 Ligovsky Ave., St. Petersburg, 191036
Phone: +7 (812) 775-75-50
V. O. Polyakova
St. Petersburg Research Institute of Phthisiopulmonology, Russian Ministry of Health
Russian Federation
Russian Federation
Viktoria O. Polyakova - Doctor of Biological Sciences, Professor, Deputy Director
2-4 Ligovsky Ave., St. Petersburg, 191036
Phone: +7 (812) 775-75-50
A. N. Muraviev
St. Petersburg Research Institute of Phthisiopulmonology, Russian Ministry of Health
Russian Federation
Russian Federation
Aleksandr N. Muraviev - Candidate of Medical Sciences, Leading Researcher, Head of Research Laboratory of Cellular Biology and Regenerative Medicine, Academic Secretary
2-4 Ligovsky Ave., St. Petersburg, 191036
Phone: +7 (812) 775-75-50
I. R. Tubeeva
St. Petersburg Research Institute of Phthisiopulmonology, Russian Ministry of Health
Russian Federation
Russian Federation
Ilona R. Tubeeva - Resident Physician
2-4 Ligovsky Ave., St. Petersburg, 191036
Phone: +7 (812) 775-75-50
S. V. Starevskaya
St. Petersburg Research Institute of Phthisiopulmonology, Russian Ministry of Health; North-Western State Medical University Named after I.I. Mechnikov
Russian Federation
Russian Federation
Svetlana V. Starevskaya Doctor of Medical Sciences, Leading Researcher, Head of Pediatric Pulmonology Unit, Associate Professor of Pediatrics and Pediatric Cardiology Department, North-Western State Medical University named after I.I.Mechnikov
2-4 Ligovsky Ave., St. Petersburg, 191036
Phone: +7 (812) 775-75-50
P. K. Yablonskiy
St. Petersburg Research Institute of Phthisiopulmonology, Russian Ministry of Health; St. Petersburg University
Russian Federation
Russian Federation
Petr K. Yablonskiy - Doctor of Medical Sciences, Professor, Director, Head of Hospital Surgery Department of Medical Faculty of St. Petersburg University
2-4 Ligovsky Ave., St. Petersburg, 191036
Phone: +7 (812) 775-75-50
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Review
For citations:
Zinchenko Yu.S., Polyakova V.O., Muraviev A.N., Tubeeva I.R., Starevskaya S.V., Yablonskiy P.K. Ways to Enhance the Diagnosis of Pulmonary Sarcoidosis (Literature Review). Tuberculosis and Lung Diseases. 2025;103(2):102-110. (In Russ.) https://doi.org/10.58838/2075-1230-2025-103-2-102-110
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