Mycobacterioses in the City of Samara
https://doi.org/10.58838/2075-1230-2025-103-5-30-35
Abstract
The objective: to study the species diversity of non-tuberculous mycobacteria detected in Samara and incidence of mycobacteriosis taking into account the patients’ immune status.
Subjects and Methods. In 2017-2024, 69 patients aged 21-86 years in whose specimens non-tuberculosis mycobacteria had been detected were examined. In 30 (43.5%) people, non-tuberculous mycobacteria were detected only once in sputum, which was assessed as carriage (Observation Group (OG)). The mycobacteriosis group (MG) included 39 (56.5%) individuals in whom the same non-tuberculous mycobacteria were detected in sputum at least twice, or once in BALF and surgical specimens.
Results. In 2023 in Samara, the incidence of pulmonary mycobacteriosis was 1.6 per 100,000 population, while prevalence made 3.4 per 100,000 population. The most frequently detected causative agents of mycobacteriosis were Mycobacterium avium complex (MAC) and M. kansasii, and of the fast-growing non-tuberculous mycobacteria, it was M. septicum. Among individuals who developed mycobacteriosis, 25.6% (10/39) were HIV positive (of which 9/10 (90%) had a CD4+ lymphocyte count below 300 cells/μl). In 1 patient, mycobacteriosis developed against during continuous administration of glucocorticosteroids for nonspecific ulcerative colitis.
About the Authors
R. Sh. Valiev
Kazan State Medical Academy, Branch of Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
Ravil Sh. Valiev - Doctor of Medical Sciences, Professor, Head of Phthisiology and Pulmonology Department.
36 Butlerova St., Kazan, 420012
Phone: + 7 (843) 233-34-87
A. N. Lezhnin
N.V. Postnikov Samara Regional Clinical TB Dispensary
Russian Federation
Russian Federation
Aleksey N. Lezhnin - Resident Physician.
154 Novo-Sadovaya St., Samara, 443068
Phone: +7 (846) 975-29-19
M. N. Kabaeva
N.V. Postnikov Samara Regional Clinical TB Dispensary
Russian Federation
Russian Federation
Maria N. Kabaeva - Head Physician.
154 Novo-Sadovaya St., Samara, 443068
Phone: +7 (846) 975-29-19
S. A. Tsarev
Samara State Medical University, Russian Ministry of Health
Russian Federation
Russian Federation
Sergey A. Tsarev - Candidate of Medical Sciences, Associate Professor of Department of Public Health and Health Care.
89 Chapaevskaya St., Samara, 443099
Phone: +7 (846) 374-10-04
N. R. Valiev
Kazan State Medical Academy, Branch of Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
Nail R. Valiev - Candidate of Medical Sciences, Associate Professor of Phthisiology and Pulmonology Department.
36 Butlerova St., Kazan, 420012
Phone: + 7 (843) 233-34-87
T. P. Persiyantseva
N.V. Postnikov Samara Regional Clinical TB Dispensary
Russian Federation
Russian Federation
Tatiana P. Persiyantseva - Head of Bacteriological Laboratory.
154 Novo-Sadovaya St., Samara, 443068
Phone: +7 (846) 975-29-19
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Review
For citations:
Valiev R.Sh., Lezhnin A.N., Kabaeva M.N., Tsarev S.A., Valiev N.R., Persiyantseva T.P. Mycobacterioses in the City of Samara. Tuberculosis and Lung Diseases. 2025;103(5):30-35. (In Russ.) https://doi.org/10.58838/2075-1230-2025-103-5-30-35
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