The Problem of Tuberculosis Relapses in the Current Epidemiological Situation
https://doi.org/10.58838/2075-1230-2026-104-1-52-57
Abstract
The objective: to study tuberculosis relapses in Kaluga Region.
Subjects and Methods. A retrospective study of all reported tuberculosis cases in Kaluga Region in 2019-2023 (n=996) was conducted. It included 817 new tuberculosis cases (New TB Cases Group) and 179 tuberculosis relapses (TB Relapses Group).
Results. Tuberculosis relapses were significantly more often detected among patients with disabilities due to other diseases (p<0.05), 52.3% of tuberculosis relapses were the cases reported 10 years or more after the cure of tuberculosis. Relapses versus new cases of tuberculosis more often had a positive result of sputum tests, (68.4% versus 58.6%, p=0.017), multiple and extensive drug resistance (46.9% and 3.4% versus 16.4% and 0.9%, p<0.05), and lung tissue decay (61.6% versus 46.95%, p<0.001). In the group of tuberculosis relapses, lethal outcomes from tuberculosis were more frequently reported (6.7% versus 2.8%; p=0.010), while in the group of new cases, postmortem diagnosis of tuberculosis was more frequent (6.0% versus 1.1%, p=0.007), which indicated untimely diagnosis of the disease.
About the Authors
I. S. Lapshina
Kaluga State University Named after K.E. Tsiolkovsky
Russian Federation
Russian Federation
Irina S. Lapshina, Candidate of Medical Sciences, Associate Professor of Internal Medicine Department of Medical Institute
26 Stepana Razina St., Kaluga, 248023
E. B. Tsybikova
Russian Research Institute of Health, Russian Ministry of Health
Russian Federation
Russian Federation
Erzheni B. Tsybikova, Doctor of Medical Sciences,
Chief Researcher of Public Health and Demography Department
11 Dobrolyubova St., Moscow, 127254
V. A. Pimenova
Kaluga State University Named after K.E. Tsiolkovsky
Russian Federation
Russian Federation
Viktoriya A. Pimenova, Student of Medical Institute
26 Stepana Razina St., Kaluga, 248023
A. Yu. Ulitina
Kaluga State University Named after K.E. Tsiolkovsky
Russian Federation
Russian Federation
Anastasia Yu. Ulitina, Student of Medical Institute
26 Stepana Razina St., Kaluga, 248023
E. A. Elistratov
Kaluga State University Named after K.E. Tsiolkovsky
Russian Federation
Russian Federation
Evgeniy A. Elistratov, Student of Medical Institute
26 Stepana Razina St., Kaluga, 248023
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Review
For citations:
Lapshina I.S., Tsybikova E.B., Pimenova V.A., Ulitina A.Yu., Elistratov E.A. The Problem of Tuberculosis Relapses in the Current Epidemiological Situation. Tuberculosis and Lung Diseases. 2026;104(1):52-57. (In Russ.) https://doi.org/10.58838/2075-1230-2026-104-1-52-57
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