Surgical Aspects of Diagnosis and Treatment of Pulmonary Mycobacteriosis
https://doi.org/10.58838/2075-1230-2026-104-1-65-71
Abstract
The objective: to study results of using surgical methods for diagnosis and treatment of pulmonary mycobacteriosis.
Subjects and Methods. The study was conducted in Thoracic Surgery Department of National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health, from 2022 to 2024. The data of 29 patients with pulmonary mycobacteriosis were analyzed. All those patient underwent surgical treatment, 22 patients had it for therapeutic and diagnostic purposes, and 7 for therapeutic purposes only. Non-tuberculous mycobacteria (NTMB) from specimens were detected by fluorescence microscopy, molecular genetic methods, and culture on liquid nutrient media. When isolating NTMB culture, mass spectrometry was used for species identification.
Results. In 22 patients with suspected pulmonary mycobacteriosis without bacteriological confirmation before surgery, 16 segmentectomies, 4 lobectomies, and 2 combined resections were performed. By culture of surgical specimens on liquid nutrient media, growth of NTMB was obtained in 9/22 (40.9%) patients. The species spectrum of NTMB included M. chimaera intracellulare group, M. xenopi, and M. kansasii (3 cases each, 33.3%). Using the molecular genetic method, NTMBs were obtained in 20/22 (91%) patients.
About the Authors
M. V. Sinitsyn
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health; Pirogov Russian National Research Medical University, Russian Ministry of Health
Russian Federation
Russian Federation
Mikhail V. Sinitsyn, Doctor of Medical Sciences, Deputy Head Physician for Surgery, Professor of Phthisiology Department
Build. 2, 4 Dostoevskiy St., Moscow, 127473;
Phone: +7 (495) 631 -15-15
D. M. Kutuzova
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health
Russian Federation
Russian Federation
Darya M. Kutuzova, Junior Researcher of Research Department of Differential Diagnostics and Treatment of Tuberculosis and Concurrent Infections
Build. 2, 4 Dostoevskiy St., Moscow, 127473;
Phone: +7 (495) 631 -15-15
V. N. Zimina
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health; Kemerovo State Medical University, Russian Ministry of Health
Russian Federation
Russian Federation
Vera N. Zimina, Doctor of Medical Sciences, Leading Researcher of Infectious Diseases Department, Professor of Phthisiology Department
Build. 2, 4 Dostoevskiy St., Moscow, 127473;
Phone: +7 (495) 631 -15-15
I. A. Vasilyeva
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health; Pirogov Russian National Research Medical University, Russian Ministry of Health
Russian Federation
Russian Federation
Irina A. Vasilyeva, Doctor of Medical Sciences, Professor,
Director Head of Phthisiology Department
Build. 2, 4 Dostoevskiy St., Moscow, 127473;
Phone: +7 (495) 631 -15-15
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For citations:
Sinitsyn M.V., Kutuzova D.M., Zimina V.N., Vasilyeva I.A. Surgical Aspects of Diagnosis and Treatment of Pulmonary Mycobacteriosis. Tuberculosis and Lung Diseases. 2026;104(1):65-71. (In Russ.) https://doi.org/10.58838/2075-1230-2026-104-1-65-71
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