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Multidrug Resistant Tuberculosis: Postponed Treatment Outcomes

https://doi.org/10.58838/2075-1230-2026-104-2-33-37

Abstract

The objective: to evaluate postponed treatment outcomes in the patients with multidrug resistant tuberculosis (MDR TB) detected during preventive screening and by self-referral to a medical unit.

Subjects and Methods. Data from in-patient records of 147 patients were retrospectively analyzed. All those patients had MDR TB with a positive result of sputum tests and underwent treatment in the Grondo Regional Clinical Center of Phthisiology. 

Results. 103/147 (70.1%) cases of pulmonary tuberculosis were detected by screening, while 44/147 (29.9%) were detected by self-referral, p<0.001. It was possible to trace treatment outcomes in 114 patients only.  Sputum conversion was achieved in the patients detected by screening within 6 months (inclusive) which was statistically significantly more frequently than among patients identified during self-referral (61/82 (74.4%) versus 15/32 (46.9%), p≤0.05). Over 18 months, successful treatment outcomes were achieved statistically significantly more often in patients detected by screening (26/82 (31.7%), 95% CI 22.6-42.4) versus self-referral (4/32 (12.5%), 95% CI 5.0-28.1), p=0.046. Of 114 patients, a favorable treatment outcome was achieved in 86 (75.4%) 95% CI (66.8-82.4) patients, regardless of the duration of treatment and the way of tuberculosis detection: 65 patients detected by screening and 21 patients detected by self-referral.

About the Author

T. Yu. Liashchuk
Grodno State Medical University
Belarus

Tatiana Yu. Liashchuk - Candidate of Medical Sciences, Senior Teacher of X-Ray Diagnostic Department

80 Gorkogo St.,Grodno, 230009

Phone: + 375 (152) 44-36-52



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For citations:


Liashchuk T.Yu. Multidrug Resistant Tuberculosis: Postponed Treatment Outcomes. Tuberculosis and Lung Diseases. 2026;104(2):33-37. (In Russ.) https://doi.org/10.58838/2075-1230-2026-104-2-33-37

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)