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TUBERCULOSIS SPONDYLITIS IN CHILDREN: COMPARATIVE ANALYSIS OF TWO BACTERIOLOGICALLY VERIFIED CLINICAL COHORTS

Abstract

Clinical and X-ray manifestations of spondylites caused by strains of M. bovis BCG and non-vaccination strains of M. tuberculosis complex have been compared in children. Significant di}erences between groups have been found only in the number of a}ected spondyles, value of ESR and leukocytes quantity. No di}erence has been found in the level of the lesion, frequency of specific abscesses, neurologic disorders and hyperergic reaction to 2TU Mantoux tests.

Publication type: comparison of clinical cohorts. Level of evidence – 3. 

About the Authors

A. Yu. Mushkin
St. Petersburg Research Institute of Phthisiopulmonology
Russian Federation
St. Petersburg


D. B. Malamashin
St. Petersburg Research Institute of Phthisiopulmonology
Russian Federation
St. Petersburg


M. N. Bakin
St. Petersburg Research Institute of Phthisiopulmonology
Russian Federation
St. Petersburg


V. A. Golubev
St. Petersburg Research Institute of Phthisiopulmonology
Russian Federation
St. Petersburg


References

1. Malyarova E.Yu., Galkina E.V., Mushkin А.Yu. et al. Generalized mycobacterial diseases with skeletal lesions in primary immune deficiency. Tuberkulez u detei i podrostkov. Sb. materialov nauch.-prakt. konf. RАMN i TSNIIT. [Tuberculosis in children and adolescents. Coll or articles of scientific practical conference of RAMS and CTRI]. Moscow, 2009, pp. 191-195. (In Russ.)

2. Mushkin А.Yu., Malyarova E.Yu., Malamashin D.B. et al. 14 year monitoring of bacteriological verification of bone and joint tuberculosis in children. Med. Alyans, 2013, no. 2, pp. 49-52. (In Russ.)

3. Appendix no. 5 to Edict no. 109 by RF MoH as of 21.03.2003 On Improvement of TB Control Measures in the Russian Federation. (In Russ.)

4. Appendix no. 855 to the Edict by RMoHSD as of October 29, 2009: Appendix no. 4 to Edict no. 109 by RF MoH as of 21.03.2003 On Improvement of TB Control Measures in the Russian Federation. (In Russ).

5. Khirurgicheskoe lechenie kostno-sustavnogo tuberkuleza. [Surgery treatment of bone and joint tuberculosis]. Ed. by Yu.N. Levashev and A.Yu. Mushkin. St. Petersburg, 2008, 226 p.

6. Narvskaya O., Mokrousov I., Otten T., Vishnevsky B. Molecular markers: application for studies of Mycobacterium tuberculosis population in Russia. In: Trends in DNA fingerprinting research (ed. M. M. Read). Nova Science publishers, NY, USA, 2005. pp. 111-125.


Review

For citations:


Mushkin A.Yu., Malamashin D.B., Bakin M.N., Golubev V.A. TUBERCULOSIS SPONDYLITIS IN CHILDREN: COMPARATIVE ANALYSIS OF TWO BACTERIOLOGICALLY VERIFIED CLINICAL COHORTS. Tuberculosis and Lung Diseases. 2015;(8):15-20. (In Russ.)

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)