INTEGRATED ASSESSMENT OF BRONCHIAL PATENCY IN ACTIVE PULMONARY TUBERCULOSIS TREATMENT BEFORE AND AFTER THE IN-PATIENT TREATMENT
Abstract
Changes in the bronchial patency, its correlation with initial manifestations of bronchial obstruction and with the rate of clinical and X-ray changes of tuberculosis disease have been assessed in 215 patients su}ering from active pulmonary tuberculosis. The administered therapy improved the bronchial patency only in 40.5% of pulmonary tuberculosis patients with bronchial obstruction. Functional changes were more often observed in the patients with initially minor or moderate obstructive disorders. Correlation between functional changes has been found including changes in viscous respiratory resistance and changes in tuberculosis disease. Changes in viscous respiratory resistance during the treatment of pulmonary tuberculosis changes with bronchial obstruction can be considered as an indicator of tuberculosis disease. The obtained results provide the evidence of the stable and clear influence of bronchial obstruction on clinical and x-ray changes of pulmonary tuberculosis, which points out at the need of monitoring the respiratory function and timely prescription of comprehensive broncholytic therapy to pulmonary tuberculosis patients.
About the Authors
E. M. Zhukova
Novosibirsk Tuberculosis Research Institute
Russian Federation
Novosibirsk
Russian Federation
Novosibirsk
V. A. Krasnov
Novosibirsk Tuberculosis Research Institute
Russian Federation
Novosibirsk
Russian Federation
Novosibirsk
L. G. Vokhminova
Novosibirsk Tuberculosis Research Institute
Russian Federation
Novosibirsk
Russian Federation
Novosibirsk
References
1. Global'naya strategiya diagnostiki, lecheniya i profilaktiki khronicheskoy obstruktivnoy bolezni legkikh (peresmotr 2011). [Russ. Ed.: Global Strategy for Diagnosis, Management, and Prevention of COPD (revision as of 2011)]. Translated from English by A.S. Belyavsky. Moscow, Rossiyskoye Respiratornoye Obschestvo Publ., 2012, 80 p.
2. Zhukova E.M., Vokhminova L.G., Klimova I.P. et al. Diagnostic value of formed oscillations technique for detection of bronchial obstruction. Probl. Tub., 2003, no. 2, pp. 19-22. (In Russ.)
3. Zil'ber N.А., Kuznetsova V.K. Respiratory mechanics in oscillating flow in chronic bronchitis patients. Probl. Pulmonologii, 1985, Issue 9. pp. 210-218. (In Russ.)
4. Krasnov V.А., Zhukova E.M., Vokhminova L.G. The technique of forced oscillations in the detection of bronchial obstruction in pulmonary tuberculosis patients. Probl. Tub., 2005, no. 12, pp. 29-31. (In Russ.)
5. Nefedov V.B., Smirnova D.G. Changes in the pulmonary functions during chemotherapy of destructive pulmonary tuberculosis patients. Probl. Tub., 1996, no. 6, pp. 60-64. (In Russ.)
6. Priymak A.A., Evfimyevskiy V.P. Klinicheskoe znachenie metoda krivoy potok-ob'em forsirovannogo vydokha v diagnostike ventilyatsionnoy nedostatochnosti u bol'nykh tuberkulezom legkikh: Metod. rekomendatsii. [Clinical value of forced expiration volume-flow curve technique for diagnostics of ventilation insufficiency in pulmonary tuberculosis patients. Guidelines]. Moscow, 1996, 14 p.
7. Stepanyan I.E. Disorders of bronchial patency in patients suffering from pulmonary tuberculosis. Tub., 2013, no. 4, pp. 6-11. (In Russ.)
8. Shmelev E.I. Bronchial obstruction in respiratory diseases and bronchodilators. Pulmonoloiya, 2006, no. 6, pp. 112-117. (In Russ.)
9. Scherbakova G.V. Evolyutsiya bronkhoobstruktivnogo sindroma u bol'nykh aktivnym tuberkulezom legkikh. Diss. kand. med. nauk. [Evolution of the bronchial obstruction syndrome in active pulmonary tuberculosis patients. Cand. Diss.]. Moscow, 2008, 18 p.
10. Demedts M. Clinical applications of forced oscillation technique. Chest, 1991, vol. 99, pp. 795-796.
Review
For citations:
Zhukova E.M., Krasnov V.A., Vokhminova L.G. INTEGRATED ASSESSMENT OF BRONCHIAL PATENCY IN ACTIVE PULMONARY TUBERCULOSIS TREATMENT BEFORE AND AFTER THE IN-PATIENT TREATMENT. Tuberculosis and Lung Diseases. 2015;(8):32-37. (In Russ.)
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