ESTIMATION OF THE SPREAD OF LATENT TUBERCULOSIS INFECTION IN TUBERCULOSIS FACILITY EMPLOYEES
https://doi.org/10.21292/2075-1230-2014-0-5-66-68
Abstract
The paper gives the results of examination using QuantiFERON-TB and diaskintest in 180 employees of the Novosibirsk Research Institute of Tuberculosis. Latent tuberculosis infection was detected in almost one-third of the employees. The closest proximity to the patient (phthisiatricians and middle-level medical personnel) and a long (more than 10-year) service are important infection factors for the employees. Diaskintest and QuantiFERON-TB show a moderate agreement, more on a negative result. The obtained data on the conversion and reversion of QuantiFERON-TB during retesting are ambiguous and agree with those of available foreign publications.
About the Authors
M. M. Zorina
ФГБУ «Новосибирский научно-исследовательский институт туберкулеза» Минздрава России
Russian Federation
Russian Federation
P. N. Filimonov
ФГБУ «Новосибирский научно-исследовательский институт туберкулеза» Минздрава России
Russian Federation
Russian Federation
I. G. Felker
ФГБУ «Новосибирский научно-исследовательский институт туберкулеза» Минздрава России
Russian Federation
Russian Federation
A. V. Maltsev
ФГБУ «Новосибирский научно-исследовательский институт туберкулеза» Минздрава России
Russian Federation
Russian Federation
References
1. Волченков Г. В. Национальное руководство по противотуберкулезному инфекционному контролю республики Таджикистан // Минздрав Республики Таджикистан. - Душанбе, 2011.
2. Arshad S., Bavan L., Gajari K. et al. Active screening at entry for tuberculosis among new immigrants: a systematic review and meta-analysis // Europ. Respir. J. - 2010. - Vol. 35, № 6. - P. 1336-1345.
3. Baussano I., Nunn P., Williams B. et al. Tuberculosis among health care workers // Emerging Infectious Disease journal. - 2011. - Vol. 17, № 3. - P. 488-494.
4. Catanzaro A., Daley C. A summary of the Third Global Interferon-γ Release Assay Symposium // Infection Control and Hospital Epidemiology. - 2013 - Vol. 34, № 6. - P. 619-624.
5. Comstock G. W. How much isoniazid is needed for the prevention of tuberculosis among immunocompetent adults? // Intern. J. Tub. Lung Dis. - 1999. - Vol. 3, № 10. - P. 847-850.
6. Daley C. L., Reves R. R., Beard M. A. et al. A summary of meeting proceedings on addressing variability around the cutpoint in serial interferon-γ release assay testing // Inf. Contr. Hospit. Epidemiol. - 2013. - Vol. 34, № 6. - P. 625-630.
7. Horsburgh C. R. Jr. Priorities for the treatment of latent tuberculosis infection in the United States // New Engl. J. Med. - 2004. - Vol. 350, № 20. - P. 2060.
8. Joos T. J., Miller W. C., Murdoch D. M. Tuberculin reactivity in bacilli Calmette-Guérin vaccinated populations: a compilation of international data // Int. J. Tub.Lung Dis. - 2006. - Vol. 10, № 8. - P. 883-891.
9. Nienhaus A., Costa J. T. Screening for tuberculosis and the use of a borderline zone for the interpretation of the interferon-γ release assay (IGRA) in Portuguese healthcare workers // J. Occupat. Med. Toxicol. - 2013. - Vol. 8, № 1.
10. Pai M., Joshi R., Dogra S., Mendiratta D. K. et al. Serial testing of health care workers for tuberculosis using interferon-gamma assay // Am. J. Respir. Crit. Care Med. - 2006. - Vol. 174, № 3. - P. 349-355.
11. Rieder H. L. Interventions for tuberculosis control and elimination // Int. Union Against Tub. Lung Dis. - Paris, 2002.
12. Ringshausen F. C., Schablon A., Nienhaus A. Interferon-gamma release assays for the tuberculosis serial testing of health care workers: a systematic review // J. Occupat. Med. Toxicol. - 2012. - Vol. 7, № 4.
13. Shu C. C., Wu V. C., Yang F. J. et al. Dynamic changes in positive interferon-gamma release assay in a dialysis population: An observational cohort study // J. Infect. - 2013. - Vol. 67, № 6. - P. 529-535.
14. Trajman A., Steffen R. E., Menzies D. Interferon-gamma release assays versus tuberculin skin Testing for the diagnosis of latent tuberculosis infection: An overview of the evidence // Pulmon. Med. - 2013. - Article ID 601737.
15. Walter N. D., Painter J., Parker M. et al. Persistent latent tuberculosis reactivation risk in United States immigrants // Am. J. Respirat. Crit. Care Med. - 2014. - Vol. 189, № 1. - P. 88-95.
16. World Health Organization. Global tuberculosis report 2013. Available at: http://www.who.int/tb/publications/global_report/en/. Accessed: January 10, 2014.
17. Zwerling A., van den Hof S., Scholten J. et al. Interferon-gamma release assays for tuberculosis screening of healthcare workers: a systematic review // Thorax. - 2012. - Vol. 67, № 1. - P. 62-70.
Review
For citations:
Zorina M.M., Filimonov P.N., Felker I.G., Maltsev A.V. ESTIMATION OF THE SPREAD OF LATENT TUBERCULOSIS INFECTION IN TUBERCULOSIS FACILITY EMPLOYEES. Tuberculosis and Lung Diseases. 2014;(5):66-68. (In Russ.) https://doi.org/10.21292/2075-1230-2014-0-5-66-68
Views:
633
Email this article 