EXPERIENCE OF SHORT-COURSE TREATMENT IN THOSE SUFFERING FROM MULTIPLE DRUG RESISTANT TUBERCULOSIS
https://doi.org/10.21292/2075-1230-2018-96-5-36-41
Abstract
The article presents the analysis of outcomes of short course treatment of tuberculosis patients with multiple drug resistance (MDR TB), which was twice shorter compared to standard treatment (9-12 months versus 20-14 months). The efficiency of short-course and standard treatment did not differ significantly in new MDR TB cases and those previously who had limited tuberculous lesions and received no therapy with second line drugs in the past (69.2% versus 68.2%), while the default rate was twice less (13.5% versus 27%, p = 0.03). Economic efficiency of treatment: costs of drugs for short-course treatment of MDR TB were 3 times lower compared to the standard one.
About the Authors
A. A. Toktogonovа
National Phthisiology Center of the Ministry of Health
of the Kyrgyz Republi
Kyrgyzstan
Kyrgyzstan
Atyrkul A. Toktogonova – Senior Researcher
90a, Akhunbaeva St., Bishkek, 720020
Z. Dzh. Kyzаlаkovа
Chuysky Regional TB Control Center of the Ministry of Health of the Kyrgyz Republic
Kyrgyzstan
Kyrgyzstan
Zhanyl Zh. Kyzalakova – Deputy Director, Regional Coordinator for DR TB
79, Prospect Pobedy Ave., Village of Lebedinovka, Alamedinsky District, Chuyskaya Region, 722160
T. I. Petrenko
Novosibirsk Tuberculosis Research Institute
Russian Federation
Russian Federation
Tatiana I. Petrenko – Chief Researcher
81a, Okhotskaya St., Novosibirsk, 630040
T. A. Kolpаkovа
Novosibirsk State Medical University
Russian Federation
Russian Federation
Tatiana A. Kolpakova –Doctor of Medical Sciences, Associate Professor at FPK and PPS Tuberculosis Control Department
81a, Okhotskaya St., Novosibirsk, 630040
References
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Review
For citations:
Toktogonovа A.A., Kyzаlаkovа Z.D., Petrenko T.I., Kolpаkovа T.A. EXPERIENCE OF SHORT-COURSE TREATMENT IN THOSE SUFFERING FROM MULTIPLE DRUG RESISTANT TUBERCULOSIS. Tuberculosis and Lung Diseases. 2018;96(5):36-41. (In Russ.) https://doi.org/10.21292/2075-1230-2018-96-5-36-41
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