FACTORS PROVIDING IMPACT ON THE EFFICIENCY OF VALVE BRONCHIAL BLOCK IN THE COMPREHENSIVE TREATMENT OF DESTRUCTIVE PULMONARY TUBERCULOSIS WITH CONCURRENT HIV INFECTION
https://doi.org/10.21292/2075-1230-2018-96-8-25-30
Abstract
Valve bronchial block is successfully used for the healing of cavities in tuberculosis patients, including those with HIV infection.
The objective of the study: to investigate factors providing an impact on the healing of destructive changes when using valve bronchial block in the patients with TB/HIV co-infection.
Subjects and methods. Valve bronchial block was used in 68 HIV positive patients as a part of the comprehensive treatment of tuberculosis. Depending on its outcome, 2 groups of patients were identified: those in whom the cavity was healed (n = 38) and those in whom the cavity persisted (n = 30). The factors providing an impact on the efficiency of valve bronchial block in those groups were investigated.
Results. This method was the most effective in the patients who had tuberculous lesions in the upper lobes, with cavities up to 2 cm in diameter, scanty bacillary excretion, CD4 count above 250 cells/mcl, and good adherence to antiretroviral therapy, if it was indicated. The factors providing impact on destruction persistence during the valve bronchial block were the following: cavities from 4 to 7 cm, persisting moderate or massive bacillary excretion, extensive drug resistance, CD4 count below 250 cell/mcl, especially below 100 cells/mcl.
About the Authors
D. V. Krasnov
Novosibirsk Tuberculosis Research Institute; Novosibirsk State Medical University.
Russian Federation
Russian Federation
Denis V. Krasnov Doctor of Medical Sciences, Head of Tuberculosis Pulmonary Surgery Department.
81a, Okhotskaya St., Novosibirsk, 630040.
Ya. K. Petrova
Novosibirsk Tuberculosis Research Institute.
Russian Federation
Russian Federation
Yana K. Petrova Phthisiologist of Tuberculosis Pulmonary Surgery Department.
81a, Okhotskaya St., Novosibirsk, 630040.
S. V. Sklyuev
Novosibirsk Tuberculosis Research Institute; Novosibirsk State Medical University.
Russian Federation
Russian Federation
Sergey V. Sklyuev Candidate of Medical Sciences, Head of Endoscopy Department.
81a, Okhotskaya St., Novosibirsk, 630040.
E. P. Myshkova
Novosibirsk Tuberculosis Research Institute
Russian Federation
Russian Federation
Elena P. Myshkova Phthisiologist of the 2nd Pulmonary Tuberculosis Department.
81a, Okhotskaya St., Novosibirsk, 630040.
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Review
For citations:
Krasnov D.V., Petrova Ya.K., Sklyuev S.V., Myshkova E.P. FACTORS PROVIDING IMPACT ON THE EFFICIENCY OF VALVE BRONCHIAL BLOCK IN THE COMPREHENSIVE TREATMENT OF DESTRUCTIVE PULMONARY TUBERCULOSIS WITH CONCURRENT HIV INFECTION. Tuberculosis and Lung Diseases. 2018;96(8):25-30. (In Russ.) https://doi.org/10.21292/2075-1230-2018-96-8-25-30
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