THE COMPREHENSIVE ASSESSMENT OF THE EFFECTIVENESS OF ACTIVITIES AIMED TO CONTROL THE SPREAD OF HIV/TB CO-INFECTION IN NORTH-WEST RUSSIA
https://doi.org/10.21292/2075-1230-2019-97-3-6-15
Abstract
In Russia, the downward trends in tuberculosis transmission are leveled by the growing HIV infection spread. In order to improve the situation, it is necessary to know the strengths and weaknesses of tuberculosis control activities among people living with HIV. The objective of the study: the comprehensive assessment of the effectiveness of activities aimed to control the spread of HIV/TB co-infection in North-West Russia. Subjects and methods. The authors used epidemiological and clinical-diagnostic methods, ranking, correlation analysis, and expert assessment. The epidemiological and clinical analyses were based on the reporting forms of Rosstat on tuberculosis and HIV, data from analytical reports on monitoring visits and data from the questionnaires developed by the authors, for 2007-2017. The correlation between the studied parameters was assessed using Spearman's rank correlation. Results. In North-West Russia, the main tuberculosis control activities among people living with HIV, including logistical support and provision of personnel (Spearman's rank ratio (-0.32177), p < 0.05), a set of preventive measures aimed at the coverage with antiretroviral therapy, preventive treatment and screening for tuberculosis in HIV-positive people (Spearman's rank ratio (-0.03226), p > 0.05) did not provide any statistically significant impact on the spread of HIV/TB co-infection, which indicated of their imperfection and inequality. Conclusion. In the North-West of Russia, the system aimed to control the spread of HIV/TB co-infection requires some optimization.
About the Authors
Z. M. Zagdyn
St. Petersburg Research Institute of Phthisiopulmonology, St. Petersburg
Russian Federation
Candidate of Medical Sciences, Senior Researcher of Epidemiology and Statistics Department
Russian Federation
Candidate of Medical Sciences, Senior Researcher of Epidemiology and Statistics Department
E. V. Verbitskaya
Pavlov First Saint Petersburg State Medical University, St. Petersburg
Russian Federation
Candidate of Medical Sciences, Associate Professor of Clinical Pharmacology and Evidence-Based Medicine Department, Head of Department of Pharmaco-Epidemiology and Biomedical Statistics
Russian Federation
Candidate of Medical Sciences, Associate Professor of Clinical Pharmacology and Evidence-Based Medicine Department, Head of Department of Pharmaco-Epidemiology and Biomedical Statistics
E. G. Sokolovich
St. Petersburg Research Institute of Phthisiopulmonology, St. Petersburg
Russian Federation
Doctor of Medical Sciences, Professor, Deputy Director for Research
Russian Federation
Doctor of Medical Sciences, Professor, Deputy Director for Research
N. A. Belyakov
Northern-Western Regional Center for AIDS Prevention and Control, St. Petersburg
Russian Federation
Doctor of Medical Sciences, Professor, Academician of RAS, Director.
Russian Federation
Doctor of Medical Sciences, Professor, Academician of RAS, Director.
References
1. Belyakov N.А., Rassokhin V.V., Bobreshova А.S. HIV infection control and growing incidence in Russia. VICH-Infektsiya i Immunosuprssii, 2017, vol. 9, no. 2, pp. 82-90. (In Russ.)
2. Vasilyeva I.А., Belilovsky E.M., Borisov S.E., Sterlikov S.А., Sinitsyn M.V. Tuberculosis with concurrent HIV infection in the Russian Federation and the world. Tuberculosis and Lung Diseases, 2017, vol. 95, no. 9, pp. 8-18. (In Russ.) https://doi.org/10.21292/2075-1230-2017-95-9-8-18.
3. WHO, Global Tuberculosis Report (summary), 2017, Geneva, 2017. 6
4. Gusev D.А., Buzunova S.А., Yakovlev А.А., Musatov V.B., Glyzhina L.V.et al. Co-morbidities and their risk factors in HIV patients older than 40 years old. Journal Infektologii, 2017, vol. 9, no. 3, pp. 40-45. (In Russ.) https://doi.org/10. 22625/2072-6732-2017-9-3-40-45.
5. Zagdyn Z.M., Sivacheva I.L., Zverkova E.А., Beltyukov M.V., Sokolovich E.G. The role of antiretroviral therapy in the prevention of tuberculosis among people living with HIV (retrospective cohort clinical trial). Journal Infektologii, 2018, vol. 10, no. 1, pp. 89-95. (In Russ.)
6. Ivanov А.K., Shevyreva E.V., Skrynnik N.А., Tursunova N.А. Treatment of TB/HIV co-infected patients in the day center of TB dispensary. Med. Alyans, 2015, 4, pp. 53-59. (In Russ.)
7. Klevno N.I. The sensitivity of skin tests in case of tuberculosis in HIV positive children. Tuberculosis and Lung Diseases, 2014, vol. 91, no. 7, pp. 37-40. (In Russ.)
8. Kravchenko А.V., Yurin O.G., Belyaeva V.V., Pokrovskiy V.V. The treatment of the infection caused by human immunodeficiency virus in the Russian Federation. Terapevt. Arkhiv, 2009, vol. 81, no. 4, pp. 64-68. (In Russ.)
9. Mikhaylova Yu.V., Soshnikov S.S., Shikina I.B., Biragova O.K. Analysis of tuberculosis control activities impact on the epidemiological rates of tuberculosis. Sotsialnye Aspekty Zdorovya Naseleniya: Elektronny Nauchny Journal, 2015. vol. 1, no. 9, Epub., The website of Sotsialnye Aspekty Zdorovya Naseleniya Journal, Available: http://vestnik.mednet.ru. 10.03, 2018. (In Russ.)
10. Myasnikova E.B., Sagieva N.R., Zhuravlev V.Yu., Yablonskiy P.K. Nosocomial tuberculosis infection – justification of the epidemiological diagnostic concept. Meditsinsky Alyans, 2014, no. 1, pp. 6-18. (In Russ.)
11. Nechaeva O.B. Monitoring of tuberculosis and HIV infection in the Russian Federation. Med. Alfavit, 2017, vol. 3, no. 30 (327), pp. 24-33. (In Russ.)
12. Nechaeva O.B. Tuberculosis situation among HIV positive people in the Russian Federation. Tuberculosis and Lung Diseases, 2017, vol. 95, no. 3, pp. 13-19. (In Russ.)
13. Panteleev А.M., Nikulina O.V., Dracheva M.S., Panteleeva O.V. Contemporary tuberculosis diagnostic criteria in HIV patients. Med. Soviet, 2016, no. 10, pp. 120-124. (In Russ.)
14. Son I.M., Pashkevich D.D., Sterlikov S.А., Danilova I.D., Dergacheva А.V., Kucheryavaya D.А. Correlations between medical-economic and epidemiological rates with the frequency of treatment defaults in tuberculosis patients. Tuberculosis and Lung Diseases, 2016, vol. 94, no. 7, pp. 11-15. (In Russ.)
15. Starodubov V.I., Ulumbekova G.E. The Russian healthcare, problems and solutions. Orgzdrav, Novosti, Mneniya, Obuchenie, 2015, no. 1, pp. 12-27. (In Russ.)
16. Sterlikov S.А., Son I.M., Obukhova O.V. The state and upgrade of capital assets of tuberculosis control units of the Russian Federation (2012-2014). Menedzher Zdravookhraneniya, 2015, no. 9, pp. 6-12. (In Russ.)
17. Frolova O.P., Schukina I.V., Novoselova O.А., Volik M.V., Stakhanov V.А., Kazenny А.B. State of the cohort of tuberculosis patients with concurrent HIV infection in the Russian Federation, cross-sector and inter-agency cooperation when providing anti-tuberculosis care to HIV patients. Tuberculosis and Lung Diseases, 2014, no. 4, pp. 26-31. (In Russ.)
18. Tsybikova E.B., Zubova N.А. Tuberculosis preventive chemotherapy in those HIV positive in the regions of the Russian Federation with high prevalence of HIV infection. Tuberculosis and Lung Diseases, 2016, vol. 94, no. 2, pp. 16-24. (In Russ.)
19. Chebagina T.Yu., Samarina E.А., Sterlikov S.А. Tuberculosis in women staying in the penitentiary system of the Russian Federation. Zdorovye Naseleniya i Sreda Obitaniya, 2017, no. 2 (287), pp. 48-52. (In Russ.)
20. Amirkhanian Y.A. Russia’s response to the HIV/AIDS epidemic. Lancet ID, 2016, vol. 16, no. 10, pp. 1121. doi: 10.1016/S1473-3099(16)30347-4.
21. Auguste P., Tsertsvadze A., Court R., Pink J. A systematic review of economic models used to assess the cost-effectiveness of strategies for identifying latent tuberculosis in high-risk groups. Tuberculosis (Edinb.), 2016, vol. 99. pp. 81-91. doi: 10.1016/j.tube.2016.04.007.
22. Nguyen D.T.M., Bang N.D., Hung N.O., Beasley R.P., Hwang L.Y., Graviss E.A. Yield of chest radiograph in tuberculosis screening for HIV-infected persons at a district-level HIV clinic. Int. J. Tuberc. Lung Dis., 2016, vol. 20, no. 2, pp. 211-217. doi: 10.5588/ijtld.15.0705.
Review
For citations:
Zagdyn Z.M., Verbitskaya E.V., Sokolovich E.G., Belyakov N.A. THE COMPREHENSIVE ASSESSMENT OF THE EFFECTIVENESS OF ACTIVITIES AIMED TO CONTROL THE SPREAD OF HIV/TB CO-INFECTION IN NORTH-WEST RUSSIA. Tuberculosis and Lung Diseases. 2019;97(3):6-15. (In Russ.) https://doi.org/10.21292/2075-1230-2019-97-3-6-15
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