Latent tuberculosis infection among university students
https://doi.org/10.21292/2075-1230-2020-98-3-27-31
Abstract
Objective: to study the prevalence of latent tuberculosis infection (LTBI) among university students, to evaluate the effectiveness of preventive treatment in students with LTBI.
Subjects and methods. In 2016-2019, the three-stage study was conducted that enrolled all university students in the city of Stavropol.
In 2016-2017 during the first stage of the study, 4,139 students had tests with tuberculous recombinant allergen (TRA).
At the second stage of the study, 141 medical files of students with positive results of TRA tests were retrospectively analyzed, all students were followed up and 133 of them underwent preventive treatment.
In 2018-2019 at the third stage of the study, the long-term results of preventive treatment were evaluated.
Results. Tests with TRA allowed detecting LTBI and defining indications for preventive treatment with anti-tuberculosis drugs. Among 133 students with LTBI who had preventive treatment, there were no cases of tuberculosis; sensitivity to TRA decreased, which manifested by a decreased induration size during the control test. Thus, in 36 months of follow-up over 83 patients with hyperergic reaction, it persisted only in 4 of them.
About the Authors
O. D. Baranova
Regional Clinical TB Dispensary
Russian Federation
Russian Federation
Olga D. Baronova - Candidate of Medical Sciences, Deputy Head Doctor for Out-Patient Medical Care.
56, Dostoevskiy St., Stavropol, 355019, Phone/Fax: +7 (8652) 28-76-68; +7 (8652) 28-69-52
V. A. Аksenova
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
Russian Federation
Russian Federation
Valentina A. Aksenova - Doctor of Medical Sciences, Professor, Head of Children and Adolescents Tuberculosis Department.
Build. 2, 4, Dostoevskiy St., Moscow, 127473
N. I. Klevno
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
Russian Federation
Russian Federation
Nadezhda I. Klevno - Doctor of Medical Sciences, Professor, Leading Researcher of Children and Adolescents Department.
Build. 2, 4, Dostoevskiy St., Moscow, 127473
V. S. Odinets
Regional Clinical TB Dispensary
Russian Federation
Russian Federation
Vasiliy S. Odinets - Candidate of Medical Sciences, Head Physician.
56, Dostoevskiy St., Stavropol, 355019
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Review
For citations:
Baranova O.D., Аksenova V.A., Klevno N.I., Odinets V.S. Latent tuberculosis infection among university students. Tuberculosis and Lung Diseases. 2020;98(3):27-31. (In Russ.) https://doi.org/10.21292/2075-1230-2020-98-3-27-31
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