Preview

Tuberculosis and Lung Diseases

Advanced search

E-cigarette or vaping use-associated lung injury

https://doi.org/10.21292/2075-1230-2022-100-4-52-61

Abstract

This literature review presents data from 57 publications on vaping and e-cigarette-associated lung injury or EVALI (e-cigarette or vaping use-associated lung injury) that was first reported in 2019. The article describes the epidemiology of EVALI, the mechanism of injuring effects of vaping on the lungs, clinical signs, diagnosis and diagnostic criteria, therapy and subsequent management of patients with EVALI.

About the Authors

M. А Karpenko
RUDN University
Russian Federation

Maksim A. Karpenko, Assistant of Pediatric Department

6, Miklukho-Maklaya St., Moscow, 117198

Phone: +7 (495) 154-03-33



D. Yu. Ovsyannikov
RUDN University
Russian Federation

Dmitry Yu. Ovsyannikov, Doctor of Medical Sciences, Head of Pediatric Department

6, Miklukho-Maklaya St., Moscow, 117198

Phone: +7 (495) 154-03-33



P. А. Frolov
RUDN University
Russian Federation

Pavel A. Frolov, Assistant of Pediatric Department

6, Miklukho-Maklaya St., Moscow, 117198

Phone: +7 (495) 154-03-33



T. I. Nikiforova
Children Infectious Clinical Hospital
Russian Federation

Tatiana I. Nikiforova, Pediatrician

91/3, Kurashova St., Yakutsk, 677005

Phone: +7 (411) 243-06-11



M. V. Khandy
M. K. Ammosov North-Eastern Federal University
Russian Federation

Maria V. Khandy, Doctor of Medical Sciences, Professor, Professor of Propedeutics of Internal Diseases Department

42, Kulakovskogo St., Yakutsk, 677000

Phone: +7 (411) 235-20-90



References

1. Belyashova M.А., Ovsyannikov D.Yu., Zaytseva А.S., Daniel-Аbu M., Eliseeva T.I. Long term home oxygen therapy in children: to whom, when, how? Pediatriya, 2018, vol. 97, no. 6, pp. 133-140. (In Russ.)

2. Vinokurov А.S., Zyuzya Yu.R., Yudin А.L. Evolution of follow up CT signs in patients with COVID-19 in early stage. Luchevaya Diagnostika I Terapiya, 2020, vol. 11, no. 2, pp. 76-88. (In Russ.) http://dx.doi.org/10.22328/2079-5343-202011-2-76-88.

3. Ovsyannikov D.Yu., Dukhanin А.S. Peculiarities of mucoactive therapy in pediatric practice. Voprosy Prakticheskoy Pediatrii, 2016, vol. 11, no. 4, pp. 24-32. (In Russ.)

4. Federal Law as of July 22, 2020 On Amendments to Certain Legislative Acts of the Russian Federation on the Issue of Protecting Health of Citizens from Consequences of Consumption of Nicotine-Containing Products. (In Russ.) http://publication.pravo.gov.ru/Document/View/0001202007310084.

5. Aberegg S.K., Cirulis M.M., Maddock S.D., Freeman A., Keenan L.M., Pirozzi C.S., Raman S.M., Schroeder J., Mann H., Callahan S.J. Clinical, bronchoscopic, and imaging findings of E-cigarette, or vaping, product use-associated lung injury among patients treated at an Academic Medical Center. JAMA Netw Open, 2020, vol. 3, no. 11, pp. e2019176. doi: 10.1001/jamanetworkopen.2020.19176. PMID: 33156346; PMCID: PMC7648253.

6. Allen J.G., Flanigan S.S., LeBlanc M., Vallarino J., MacNaughton P., Stewart J.H., Christiani D.C. Flavoring Chemicals in Ecigarettes: Diacetyl, 2,3-pentanedione, and acetoin in a sample of 51 products, including fruit-, candy-, and cocktail-flavored e-cigarettes. Environ. Health. Perspect., 2016, vol. 124, no. 6, pp. 733-739.

7. Beasley M.B., Franks T.J., Galvin J.R., Gochuico B., Travis D.W. Acute fibrinous and organizing pneumonia: a histological pattern of lung injury and possible variant of diffuse alveolar damage. Arch. Pathol. Lab. Med., 2002, vol. 126, pp. 1064-1070.

8. Beattie J.R., Schock B.C. Identifying the spatial distribution of vitamin E, pulmonary surfactant and membrane lipids in cells and tissue by confocal Raman microscopy. Methods Mol. Biol., 2009, vol. 579, pp. 513-535.

9. Belok S.H., Parikh R., Bernardo J., Kathuria H. E-cigarette, or vaping, product use-associated lung injury: a review. Pneumonia, 2020, 12, 12. https://doi.org/10.1186/s41479-020-00075-2.

10. Blagev D.P., Harris D., Dunn A.C., Guidry D.W., Grissom C.K., Lanspa M.J. Clinical presentation, treatment, and short-term outcomes of lung injury associated with e-cigarettes or vaping: a prospective observational cohort study. Lancet, 2019, vol. 394, no. 10214, pp. 2073-2083.

11. Blount B.C., Karwowski M.P., Morel-Espinosa M., Rees J., Sosnoff C., Cowan E., Gardner M., Wang L., Valentin-Blasini L., Silva L., De Jesús V.R., Kuklenyik Z., Watson C., Seyler T., Xia B., Chambers D., Briss P., King B.A., Delaney L., Jones C.M., Baldwin G.T., Barr J.R., Thomas J., Pirkle J.L. Evaluation of Bronchoalveolar lavage fluid from patients in an outbreak of E-cigarette, or Vaping, product use-associated lung injury – 10 states, August-October 2019. MMWR Morb. Mortal. Wkly Rep., 2019, vol. 68, no. 45, pp. 1040-1041.

12. Butt Y.M., Smith M.L., Tazelaar H.D., Vaszar L.T., Swanson K.L., Cecchini M.J., Boland J.M., Bois M.C., Boyum J.H., Froemming A.T., Khoor A., Mira-Avendano I., Patel A., Larsen B.T. Pathology of Vaping-Associated Lung Injury. New Engl. J. Med., 2019, vol. 381, pp. 1780-1781.

13. Choe J., Chen P., Falk J.A., Nguyen L., Ng D., Parimon T., Ghandehari S. A Case series of vaping-associated lung injury requiring mechanical ventilation. Crit. Care Explorations, 2020, vol. 2, pp. e0079.

14. Chun L.F., Moazed F., Calfee C.S., Matthay M.A., Gotts J.E. Pulmonary toxicity of e-cigarettes. Am. J. Physiol. Lung Cell. Mol. Physiol., 2017, vol. 313, no. 2, pp. 193-206.

15. Consumer Advocates for Smoke Free Alternatives Association. A Historical timeline of electronic cigarettes. Accessed 4/7/21. http://www.casaa.org/historical-timeline-of-electronic-cigarettes

16. Cullen K.A., Ambrose B.K., Gentzke A.S., Apelberg B.J., Jamal A., King B.A. Notes from the field: use of electronic cigarettes and any tobacco product among middle and high school students ‒ United States, 2011-2018. Weekly, 2018, vol. 67, no. 45, pp. 1276-1277.

17. Giroud C., de Cesare M., Berthet A., Varlet V., Concha-Lozano N., Favrat B. Ecigarettes: a review of new trends in Cannabis use. Int. J. Environ. Res. Public. Health, 2015, vol. 12, no. 8, pp. 9988-10008.

18. Goniewicz M.L., Knysak J., Gawron M., Kosmider L., Sobczak A., Kurek J., Prokopowicz A., Jablonska-Czapla M., Rosik-Dulewska C., Havel C., Jacob P 3rd, Benowitz N. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob. Control, 2014, vol. 23, no. 2, pp. 133-139.

19. Gotts J.E., Jordt S.E., McConnell R., Tarran R. What are the respiratory effects of e-cigarettes? BMJ, 2019, vol. 366, pp. 1-16.

20. Grana R., Benowitz N., Glantz S.A. E-cigarettes: a scientific review. Circulation, 2014, vol. 129, no. 19, pp. 19728-19736.

21. Hashim M.J. Patient-centered communication: basic skills. Am. Fam. Physician., 2017, vol. 95, no. 1, pp. 29-34.

22. Henry T.S., Kanne J.P., Kligerman S.J. Imaging of vaping-associated lung disease. New Engl. J. Med., 2019, vol. 381, pp. 1486-1487.

23. Hutzler C., Paschke M., Kruschinski S., Henkler F., Hahn J., Luch A. Chemical hazards present in liquids and vapors of electronic cigarettes. Arch. Toxicol., 2014, vol. 88, no. 7, pp. 1295-1308.

24. ICD-10-CM Official Coding Guidelines – Supplement, Coding encounters related to E-cigarette, or Vaping, Product Use, Post Date: October 17, 2019. https://www.hhs.gov/guidance/document/icd-10-cm-official-coding-guidelines-supplement-coding-encounters-related-e-cigarette-or-0.

25. ICD-10-CM Official Guidelines for Coding and Reporting, FY 2021, (October 1, 2020 ‒ September 30, 2021). https://www.cdc.gov/nchs/data/icd/10cmguidelines-FY2021.pdf.

26. Iskandar A.R., Zanetti F., Marescotti D., Titz B., Sewer A., Kondylis A., Leroy P., Belcastro V., Torres L.O., Acali S., Majeed S., Steiner S., Trivedi K., Guedj E., Merg C., Schneider T., Frentzel S., Martin F., Ivanov N.V., Peitsch M.C., Hoeng J. Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESH technology. Arch. Toxicol., 2019, vol. 93, no. 11, pp. 3229-3247.

27. Jain R.B. Concentrations of cadmium, lead, and mercury in blood among US cigarettes, cigars, electronic cigarettes, and dual cigarette-e-cigarette users. Environ. Pollut., 2019, vol. 251, pp. 970-974.

28. Jatlaoui T.C., Wiltz J.L., Kabbani S., Siegel D.A., Koppaka R., Montandon M., Adkins S.H., Weissman D.N., Koumans E.H., O'Hegarty M., O'Sullivan M.C., Ritchey M.D., Chatham-Stephens K., Kiernan E.A., Layer M., Reagan-Steiner S., Legha J.K., Shealy K., King B.A., Jones C.M., Baldwin G.T., Rose D.A., Delaney L.J., Briss P., Evans M.E. Update: interim guidance for health care providers for managing patients with suspected e-cigarette, or Vaping, product use-associated lung injury ‒ United States, November 2019. MMWR Morb. Mortal. Wkly Rep., 2019, vol. 68, no. 46, pp. 1081-1086.

29. Kaur G., Lungarella G., Rahman I. SARS-CoV-2 COVID-19 susceptibility and lung inflammatory storm by smoking and vaping. J. Inflamm., 2020, vol. 17, pp. 21. https://doi.org/10.1186/s12950-020-00250-8.

30. Kim J., Doo K., Jang H. Acute fibrinous and organizing pneumonia: Imaging features, pathologic correlation, and brief literature review. Radiol. Case Rep., 2018, vol. 13, no. 4, pp. 867–870. http://doi.org/10.1016/j.radcr.2018.04.028.

31. Kligerman S.J., Kay F.U., Raptis C.A., Henry T.S., Sechrist J.W., Walker C.M., Vargas D.B., Filev P.D., Chung M.S., Digumarthy S.R., Ropp A.M., Mohammed T.L., Pope K.W., Marquis K.M., Chung J.H., Kanne J.P. CT Findings and patterns of electronic cigarette or vaping product use-associated lung injury (EVALI), a multicenter cohort of 160 cases. Chest, 2021, S0012-3692(21)00862-X. doi: 10.1016/j.chest.2021.04.054. Epub ahead of print. PMID: 33957099.

32. Kosmider L., Sobczak A., Fik M., Knysak J., Zaciera M., Kurek J., Goniewicz M.L. Carbonyl compounds in electronic cigarette vapors: effects of nicotine solvent and battery output voltage. Nicotine Tob. Res., 2014, vol. 16, no. 10, pp. 1319-1326.

33. Kosmider L., Sobczak A., Prokopowicz A., Kurek J., Zaciera M., Knysak J., Smith D., Goniewicz M.L. Cherry-flavoured electronic cigarettes expose users to the inhalational irritant, benzaldehyde. Thorax, 2016, vol. 71, no. 4, pp. 376-377.

34. Layden J.E., Ghinai I., Pray I., Kimball A., Layer M., Tenforde M.W., Navon L., Hoots B., Salvatore P.P., Elderbrook M., Haupt T., Kanne J., Patel M.T., Saathoff-Huber L., King B.A., Schier J.G., Mikosz C.A., Meiman J. Pulmonary illness related to e-cigarette use in illinois and wisconsin ‒ final report. N. Engl. J. Med., 2020, vol. 382, no. 10, pp. 903-916. doi: 10.1056/NEJMoa1911614. Epub 2019 Sep 6. PMID: 31491072.

35. Maddock S.D., Cirulis M.M., Callahan S.J., Keenan L.M., Pirozzi C.S., Raman S.M., Aberegg S.K. Pulmonary Lipid-Laden Macrophages and Vaping. N. Engl. J. Med., 2019, vol. 381, no. 15, pp. 1488. Epub 2019 Sep 6. doi: 10.1056/NEJMc1912038.

36. Madison M.C., Landers C.T., Gu B.H., Chang C.Y., Tung H.Y., You R., Hong M.J., Baghaei N., Song L.Z., Porter P., Putluri N., Salas R., Gilbert B.E., Levental I., Campen M.J., Corry D.B., Kheradmand F. Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine. J. Clin. Invest., 2019, vol. 129, no. 10, pp. 4290-4304.

37. Madsen R.L., Vinther Krarup N.H., Bergmann T.K., Bærentzen S., Neghabat S., Duval L., Knudsen S.T. A Cancer that went up in smoke. Chest, 2016, vol. 149, no. 3, pp. e65-e67.

38. McCauley M., Markin C., Hosmer D. An unexpected consequence of electronic cigarette use. Chest, 2012, vol. 141, no. 4, pp. 1110-1113.

39. Mikosz C.A., Danielson M., Anderson K.N., Pollack L.A., Currie D.W., Njai R., Evans M.E., Goodman A.B., Twentyman E., Wiltz J.L., Rose D.A., Krishnasamy V., King B.A., Jones C.M., Briss P., Lozier M., Ellington S. Characteristics of patients experiencing Rehospitalization or death after hospital discharge in a Nationwide outbreak of e-cigarette, or Vaping, product use-associated lung injury ‒ United States, 2019. MMWR Morb. Mortal. Wkly Rep., 2020, vol. 68, no. 5152, pp. 1183-1188.

40. Olmedo P., Goessler W., Tanda S., Grau-Perez M., Jarmul S., Aherrera A., Chen R., Hilpert M., Cohen J.E., Navas-Acien A., Rule A.M. Metal concentrations in e-cigarette liquid and aerosol samples: thecontribution of metallic coils. Environ. Health Perspect, 2018, vol. 126, no. 2, pp. 27010.

41. Orellana-Barrios M.A., Payne D., Mulkey Z., Nugent K. Electronic cigarettes ‒ a narrative review for clinicians. Am. J. Med., 2015, vol. 128, no. 7, pp. 674-681.

42. Outbreak of lung injury associated with the use of e-cigarette, or vaping, products. [Internet]. Centers for disease control and prevention (CDC). 2020 [cited 2020 May 20]. Available: https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.html#latest-information.

43. Park H.R., O'Sullivan M., Vallarino J., Shumyatcher M., Himes B.E., Park J.A., Christiani D.C., Allen J., Lu Q. Transcriptomic response of primary human airway epithelial cells to flavoring chemicals in electronic cigarettes. Sci. Rep., 2019, vol. 9, pp. 1400.

44. Perrine C.G., Pickens C.M., Boehmer T.K., King B.A., Jones C.M., DeSisto C.L., Duca L.M., Lekiachvili A., Kenemer B., Shamout M., Landen M.G., Lynfield R., Ghinai I., Heinzerling A., Lewis N., Pray I.W., Tanz L.J., Patel A., Briss P.A. Characteristics of a multistate outbreak of lung injury associated with Ecigarette use, or Vaping ‒ United States, 2019. MMWR Morb. Mortal. Wkly Rep., 2019, vol. 68, no. 39, pp. 860-864.

45. Pertwee R.G. The pharmacology of cannabinoid receptors and their ligands: An overview: [англ.]. Intern. J. Obesity, 2006, vol. 30, pp. 13-18. doi:10.1038/sj.ijo.0803272. PMID 16570099.

46. Schier J.G., Meiman J.G., Layden J., Mikosz C.A., VanFrank B., King B.A., Salvatore P.P., Weissman D.N., Thomas J., Melstrom P.C., Baldwin G.T., Parker E.M., Courtney-Long E.A., Krishnasamy V.P., Pickens C.M., Evans M.E., Tsay S.V., Powell K.M., Kiernan E.A., Marynak K.L., Adjemian J., Holton K., Armour B.S., England L.J., Briss P.A., Houry D., Hacker K.A., Reagan-Steiner S., Zaki S., Meaney-Delman D. CDC 2019 Lung Injury Response Group. Severe pulmonary disease associated with electronic-cigarette-product use ‒ interim guidance. MMWR Morb Mortal Wkly Rep., 2019, vol. 68, no. 36, pp. 787-790. doi: 10.15585/mmwr.mm6836e2. Erratum in: MMWR Morb Mortal Wkly Rep., 2019 Sep 27;68(38):830. PMID: 31513561; PMCID: PMC6755818.

47. Scott A., Lugg S.T., Aldridge K., Lewis K.E., Bowden A., Mahida R.Y., Grudzinska F.S., Dosanjh D., Parekh D., Foronjy R., Sapey E., Naidu B., Thickett D.R. Proinflammatory effects of e-cigarette vapour condensate on human alveolar macrophages. Thorax, 2018, vol. 73, no. 12, pp. 1161-1169.

48. Siegel D.A., Jatlaoui T.C., Koumans E.H., Kiernan E.A., Layer M., Cates J.E., Kimball A., Weissman D.N., Petersen E.E., Reagan-Steiner S., Godfred-Cato S., Moulia D., Moritz E., Lehnert J.D., Mitchko J., London J., Zaki S.R., King B.A., Jones C.M., Patel A., Delman D.M., Koppaka R. Update: interim guidance for health care providers evaluating and caring for patients with suspected e-cigarette, or vaping, product use associated lung injury ‒ United States, October 2019. MMWR Morb. Mortal. Wkly Rep., 2019, vol. 68, pp. 919–927. doi: http://dx.doi.org/10.15585/mmwr.mm6841e3externalicon.

49. Taylor J., Wiens T., Peterson J., Saravia S., Lunda M., Hanson K., Wogen M., D'Heilly P., Margetta J., Bye M., Cole C., Mumm E., Schwerzler L., Makhtal R., Danila R., Lynfield R., Holzbauer S. Characteristics of e-cigarette, or Vaping, products used by patients with associated lung injury and products seized by law enforcement ‒ Minnesota, 2018 and 2019. MMWR Morb. Mortal Wkly Rep., 2019, vol. 68, no. 47, pp. 1096-1100.

50. Vardavas C.I., Anagnostopoulos N., Kougias M., Evangelopoulou V., Connolly G.N., Behrakis P.K. Short-term pulmonary effects of using an electronic cigarette: impact on respiratory flow resistance, impendence, and exhaled nitric oxide. CHEST, 2012, vol. 141, no. 6, pp. 1400-1406.

51. Wang M.P., Ho S.Y., Leung L.T., Lam T.H. Electronic cigarette use and respiratory symptoms in Chinese adolescents in Hong Kong. JAMA Pediatrics, 2016, vol. 170, no. 1, pp. 89-91.

52. Werner A.K., Koumans E.H., Chatham-Stephens K., Salvatore P.P., Armatas C., Byers P., Clark C.R., Ghinai I., Holzbauer S.M., Navarette K.A., Danielson M.L., Ellington S., Moritz E.D., Petersen E.E., Kiernan E.A., Baldwin G.T., Briss P., Jones C.M., King B.A., Krishnasamy V., Rose D.A., Reagan-Steiner S. Lung Injury Response Mortality Working Group. Hospitalizations and deaths associated with EVALI. N. Engl. J. Med., 2020, vol. 382, no. 17, pp. 1589-1598. doi: 10.1056/NEJMoa1915314. PMID: 32320569.

53. Williams M., Li J., Talbot P. Effects of model, method of collection, and topography on chemical elements and metals in the aerosol of tankstyle electronic cigarettes. Sci. Rep., 2019, vol. 9, pp. 13969.

54. Winnicka L., Shenoy M.A. EVALI and the pulmonary toxicity of electronic cigarettes: a review. J. Gen. Intern. Med., 2020, vol. 35, no. 7, pp. 2130-2135. doi: 10.1007/s11606-020-05813-2.

55. Wu D., O’Shea D.F. Potential for release of pulmonary toxic ketene from vaping pyrolysis of vitamin E acetate. Proc. Natl. Acad. Sci. USA, 2020, vol. 117, no. 12, pp. 6349-6355.

56.


Review

For citations:


Karpenko M.А., Ovsyannikov D.Yu., Frolov P.А., Nikiforova T.I., Khandy M.V. E-cigarette or vaping use-associated lung injury. Tuberculosis and Lung Diseases. 2022;100(4):52-61. (In Russ.) https://doi.org/10.21292/2075-1230-2022-100-4-52-61

Views: 2575


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)