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Analysis of Tuberculosis Fatal Risk Factors in the Patients Hospitalized with COVID-19

https://doi.org/10.58838/2075-1230-2026-104-2-26-32

Abstract

The objective: to analyze risk factors of the unfavorable course of tuberculosis detected in the patients hospitalized with suspected COVID-19.

Subjects and Methods. Of 1079 patients hospitalized with suspected COVID-19 and pneumonia, 120 case histories of patients with tuberculosis were retrospectively selected using a continuous sampling method; the fatal outcome was reported in 17.5% of cases (21/120).

Results. Chronic kidney disease, diabetes mellitus, and underweight were more common among patients with a fatal outcome. Of the laboratory data, the most significant risk factors for an unfavorable outcome were as follows: levels of hemoglobin below 110 g/l, total protein below 60.4 g/l, D-dimer above 2.21 μg/ml, and C-reactive protein above 91.9 mg/l.

About the Authors

E. A. Borodulina
Samara State Medical University, Russian Ministry of Health
Russian Federation

Elena A. Borodulina, Doctor of Medical Sciences, Professor,  Head of Phthisiology  and Pulmonology Department  

89 Chapaevskaya St., Samara, 443099

Phone: + 7(846) 374-00-11



E. V. Yakovleva
Samara State Medical University, Russian Ministry of Health
Russian Federation

Elena V. Yakovleva, Candidate of Medical Sciences, Assistant of Phthisiology and Pulmonology Department 

89 Chapaevskaya St., Samara, 443099

Phone: + 7(846) 374-00-11



S. A. Zubakina
Samara State Medical University, Russian Ministry of Health
Russian Federation

Snezhana A. Zubakina, Post-Graduate Student of Phthisiology  and Pulmonology Department  

89 Chapaevskaya St., Samara, 443099

Phone: + 7(846) 374-00-11



K. V. Zhilinskaya
Samara State Medical University, Russian Ministry of Health
Russian Federation

Kristina V. Zhilinskaya, Post-Graduate Student of Phthisiology and Pulmonology 

89 Chapaevskaya St., Samara, 443099

Phone: + 7(846) 374-00-11



E. V. Russkikh
Samara State Medical University, Russian Ministry of Health
Russian Federation

Egor V. Russkikh, Post-Graduate Student of Phthisiology and Pulmonology 

89 Chapaevskaya St., Samara, 443099

Phone: + 7(846) 374-00-11



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For citations:


Borodulina E.A., Yakovleva E.V., Zubakina S.A., Zhilinskaya K.V., Russkikh E.V. Analysis of Tuberculosis Fatal Risk Factors in the Patients Hospitalized with COVID-19. Tuberculosis and Lung Diseases. 2026;104(2):26-32. (In Russ.) https://doi.org/10.58838/2075-1230-2026-104-2-26-32

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)