SURGERY FOR DRUG-RESISTANT DESTRUCTIVE PULMONARY TUBERCULOSIS
Abstract
The paper presents the experience in surgically treating 145 patients with destructive, mainly fibrocavernous pulmonary tuberculosis. All the patients completed treatment. In the preoperative preparation, particular emphasis is laid on the promptest determination of a spectrum of pathogen susceptibility/resistance, individualized chemotherapy, and collapse therapy options. Postoperative complications occurred in 27 (18.6%) patients, fatal outcomes in 4 (2.7%). The former were recorded most frequently after pneumonectomy in 13 (37.1%) cases, the later were seen in 3 (8.6%). Sputum culture conversion was generally achieved in 111 (78%) patients, particularly in 97 (78.2%) patients with multidrug-resistant tuberculosis and in 14 (66.7%) with a broad drug resistance in the pathogen. Out of the 64 patients followed up for more than 3 years, 48 (75.0%) were in clinical and bacteriological remission.
About the Authors
S. N. Skornyakov
Ural Reseach Institute of Phthisiology
Russian Federation
Ekaterinburg
Russian Federation
Ekaterinburg
I. Ya. Motus
Ural Reseach Institute of Phthisiology
Russian Federation
Ekaterinburg
Russian Federation
Ekaterinburg
E. I. Kildyusheva
Ural Reseach Institute of Phthisiology
Russian Federation
Ekaterinburg
Russian Federation
Ekaterinburg
I. D. Medvinsky
Ural Reseach Institute of Phthisiology
Russian Federation
Ekaterinburg
Russian Federation
Ekaterinburg
A. V. Bazhenov
Ural Reseach Institute of Phthisiology
Russian Federation
Ekaterinburg
Russian Federation
Ekaterinburg
A. V. Savelyev
Ural Reseach Institute of Phthisiology
Russian Federation
Ekaterinburg
Russian Federation
Ekaterinburg
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Review
For citations:
Skornyakov S.N., Motus I.Ya., Kildyusheva E.I., Medvinsky I.D., Bazhenov A.V., Savelyev A.V. SURGERY FOR DRUG-RESISTANT DESTRUCTIVE PULMONARY TUBERCULOSIS. Tuberculosis and Lung Diseases. 2015;(3):15-21. (In Russ.)
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