Drug susceptibility testing of M. tuberculosis with the help of test system of Sensititre MycoTB TREK Diagnostics
Abstract
The article presents efficiency comparison of Sensititre test system and culture methods of Bactec 960 and Lowenstein-Jensen medium for drug susceptibility testing of tuberculosis mycobacteria.
Cultures of M. tuberculosis of 137 patients have been studied. It has been found out that the part of coinciding results is fairly big for drug susceptibility testing by test system of Sensititre MycoTB and other methods. This system has the advantages related to standard procedures and capacity of drug susceptibility testing (degree) to 12 drugs simultaneously within a short period of time (7-14 days). Drug susceptibility testing of M. tuberculosis by testing system of Sensititre MycoTB is simpler from technical point of view compared to all other systems. Sensititre MycoTB has been tested abroad and in MSPCT and certified and it can be used for the clinical practice.
About the Authors
M. V. Makarova
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Moscow
Russian Federation
Moscow
S. G. Safonova
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Moscow
Russian Federation
Moscow
L. Yu. Krylova
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Moscow
Russian Federation
Moscow
N. V. Litvinova
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Moscow
Russian Federation
Moscow
E. Yu. Nosova
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Moscow
Russian Federation
Moscow
V. I. Litvinov
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Makarova M.V., Safonova S.G., Krylova L.Yu., Litvinova N.V., Nosova E.Yu., Litvinov V.I. Drug susceptibility testing of M. tuberculosis with the help of test system of Sensititre MycoTB TREK Diagnostics. Tuberculosis and Lung Diseases. 2015;(4):42-48. (In Russ.)
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