EXTRAPULMONARY TUBERCULOSIS IN SIBERIA AND FAR EAST

Extrapulmonary tuberculosis still remains a mysterious problem greatky due to significant degree of divergence in definitions.

Materials and methods. Extrapulmonary tuberculosis incidence and its structure have been analyzed for Siberian and Far Eastern Federal Districts for the last 10 years – from 2006 to 2015.

Results. In 2006 in Siberian and Far Eastern Federal Districts there were 871 patients suffering from isolated extrapulmonary tuberculosis, the structure of the forms was as follows: tuberculosis of central nervous system (CNS) – 5.7%; bone and joint tuberculosis – 28.7%; urogenital tuberculosis – 35.9%; tuberculosis of peripheral lymph nodes – 15.8%; ocular tuberculosis – 5.2%, other forms – 8.7%. Starting from 2008 ocular tuberculosis was excluded from reporting, despite the fact that the number of such patients was almost the same as the number of CNS tuberculosis cases. 10 years later in 2015 isolated forms of tuberculosis were diagnosed in 699 (-172) people, forms were the following: CNS tuberculosis – 10.6%, double increase; bone and joint tuberculosis – 39.8%, 1.5 fold increase; urogenital tuberculosis – 24.5%, 1.5 fold decrease respectively. Number of those suffering from tuberculosis of peripheral lymph nodes remained the same – 14.2%, other forms inclusive tuberculosis of salivary glands, pancreas, gall bladder, intestine, breast, skin etc. increased respectively up to 11%.

Conclusions. The problem of extrapulmonary tuberculosis in Russia as in the whole world still needs to be resolved. Extrapulmonary tuberculosis incidence greatly depends on the number of properly trained specialists and sufficient technical facilities of dispensaries. The following changes are to be made to Form 8: firstly, urological and genital tuberculosis cases are to be recorded separately; secondly, all forms are to be recorded separately according to HIV status. 

1. Zhukova I.I., Kulchavenya E.V., Kholtobin D.P. et al. Tuberkulyoz mochepolovoy sistemy segodnya. [Tuberculosis of genitourinary system nowadays]. Urologiya, 2013, no. 1. pp. 13-16. (In Russ.)

2. Dovgopolyuk E.S., Kalacheva G.А., Mordyk А.V. et al. Tuberculosis epidemics in the children exposed to HIV infection during the perinatal period in Siberian Federal District. Sib. Med. Obozreniye, 2011, vol. 72, no. 6, pp. 47-49. (In Russ.)

3. Kulchavenya E.V., Brizhatyuk E.V., Khomyakov V.T. Extrapulmonary tuberculosis in Siberia and Far East. Tuberculosis and Lung Diseases, 2005, no. 6, pp. 23-25. (In Russ.)

4. Zhukova I.I., Kulchavenya E.V., Kholtobin D.P. et al. Tuberkulyoz mochepolovoy sistemy segodnya. [Tuberculosis of genitourinary system nowadays]. Urologiya, 2013, no. 1. pp. 13-16. (In Russ.)

5. Kulchavenya E.V., Koveshnikova E.Yu., Zhukova I.I. Clinical and epidemiological specific features of current tuberculous spondylitis. Tuberculosis and Lung Diseases, 2013, no. 1. pp. 41-45. (In Russ.)

6. Kulchavenya E.V., Brizhatyuk E.V., Khomyakov V.T. Extrapulmonary tuberculosis in Siberia and Far East. Tuberculosis and Lung Diseases, 2005, no. 6, pp. 23-25. (In Russ.)

7. Mikhaylovskiy А.M., Lepekha L.N., Erokhin V.V. Morphology of tuberculosis with concurrent HIV infection (as per autopsy data). Tuberculosis and Lung Diseases, 2014, no. 10. pp. 65-70. (In Russ.)

8. Kulchavenya E.V., Koveshnikova E.Yu., Zhukova I.I. Clinical and epidemiological specific features of current tuberculous spondylitis. Tuberculosis and Lung Diseases, 2013, no. 1. pp. 41-45. (In Russ.)

9. Nechaeva O.B., Skachkov V.V. Epidemic situation on extrapulmonary tuberculosis in the Russian Federation. Tuberculosis and Lung Diseases, 2013, no. 8. pp. 3-9. (In Russ.)

10. Mikhaylovskiy А.M., Lepekha L.N., Erokhin V.V. Morphology of tuberculosis with concurrent HIV infection (as per autopsy data). Tuberculosis and Lung Diseases, 2014, no. 10. pp. 65-70. (In Russ.)

11. Safaryan M.D., Nikolayan L.T., Аzizyan N.G. Symptoms, diagnostics and treatment of tuberculosis in HIV patients in Armenia Republic. Tuberculosis and Lung Diseases, 2014, no. 6. pp. 22-24. (In Russ.)

12. Nechaeva O.B., Skachkov V.V. Epidemic situation on extrapulmonary tuberculosis in the Russian Federation. Tuberculosis and Lung Diseases, 2013, no. 8. pp. 3-9. (In Russ.)

13. Tuberkulez v Rossiyskoy Federatsii 2012, 2013, 2014 g. Аnaliticheskiy obzor statisticheskikh pokazateley, ispolzuemykh v Rossiyskoy Federatsii i v mire. [Tuberculosis in the Russian Federation in 2011, 2013. 2014. Analytic review of statistic rates used in the Russian Federation and in the world]. Moscow, 2015, 312 p.

14. Safaryan M.D., Nikolayan L.T., Аzizyan N.G. Symptoms, diagnostics and treatment of tuberculosis in HIV patients in Armenia Republic. Tuberculosis and Lung Diseases, 2014, no. 6. pp. 22-24. (In Russ.)

15. Frolova O.P., Schukina I.V., Frolov E.G. et al. Analysis of mortality due to tuberculosis with concurrent HIV infection.Tuberculosis and Lung Diseases, 2014, no. 7. pp. 32-36. (In Russ.)

16. Tuberkulez v Rossiyskoy Federatsii 2012, 2013, 2014 g. Аnaliticheskiy obzor statisticheskikh pokazateley, ispolzuemykh v Rossiyskoy Federatsii i v mire. [Tuberculosis in the Russian Federation in 2011, 2013. 2014. Analytic review of statistic rates used in the Russian Federation and in the world]. Moscow, 2015, 312 p.

17. Frolova O.P., Schukina I.V., Frolov E.G. et al. Tuberculosis in HIV patients as a national problem. Tuberculosis and Lung Diseases, 2013, no. 10. pp. 9-12. (In Russ.)

18. Frolova O.P., Schukina I.V., Frolov E.G. et al. Analysis of mortality due to tuberculosis with concurrent HIV infection.Tuberculosis and Lung Diseases, 2014, no. 7. pp. 32-36. (In Russ.)

19. Tsybikova E.B., Vladimirov А.V. Analysis of tuberculosis and HIV mortality in the regions of the Russian Federation. Tuberculosis and Lung Diseases, 2015, no. 12. pp. 37-43. (In Russ.)

20. Frolova O.P., Schukina I.V., Frolov E.G. et al. Tuberculosis in HIV patients as a national problem. Tuberculosis and Lung Diseases, 2013, no. 10. pp. 9-12. (In Russ.)

21. Kulchavenya E. Best practice in the diagnosis and management of Urogenital Tuberculosis. Ther Adv. Urol., 2013, vol. 5, no. 3, pp. 143-151. doi: 10.1177/1756287213476128.

22. Tsybikova E.B., Vladimirov А.V. Analysis of tuberculosis and HIV mortality in the regions of the Russian Federation. Tuberculosis and Lung Diseases, 2015, no. 12. pp. 37-43. (In Russ.)

23. Kulchavenya E. Best practice in the diagnosis and management of Urogenital Tuberculosis. Ther Adv. Urol., 2013, vol. 5, no. 3, pp. 143-151. doi: 10.1177/1756287213476128.