CLINICAL CASE OF EFFECTIVE HOLISTIC TREATMENT OF BILATERIAL FIBROUS CAVERNOUS PULMONARY TUBERCULOSIS
https://doi.org/10.21292/2075-1230-2017-95-3-62-68
Abstract
The article describes the clinical case of successful treatment of a 42 year old female patient suffering from bilateral fibrous cavernous pulmonary tuberculosis with fully destroyed left lung, persistent bacillary excretion and extensive drug resistance. The treatment was complicated by poor tolerance of the used anti-tuberculosis drugs.
Multiple surgeries were applied combined with resection and collapse interventions; anti-tuberculosis drugs and their doses were prescribed individually to this patients and supplemented by adjuvant therapy.
The course of the disease stabilized, sputum converted and cavities were healed.
About the Authors
G. Yu. MarfinaRussian Federation
Candidate of Medical Sciences, Senior Researcher of Thoracic Surgery Department,
2-4, Ligovsky Ave., St. Petersburg, 191036
K. B. Vladimirov
Russian Federation
Candidate of Medical Sciences, Thoracic Surgeon of Tuberculosis Pulmonary Surgical Department of the Hospital, Penal Colony no. 78,
2-4, Ligovsky Ave., St. Petersburg, 191036
G. G. Kudryashov
Russian Federation
Surgeon of Thoracic Surgery Department,
2-4, Ligovsky Ave., St. Petersburg, 191036
E. V. Istomina
Russian Federation
Phthisiologist of Thoracic Surgery Department,
2-4, Ligovsky Ave., St. Petersburg, 191036
A. O. Avetisyan
Russian Federation
Candidate of Medical Sciences, Head of Thoracic Surgery Department,
2-4, Ligovsky Ave., St. Petersburg, 191036
References
1. Balasanyants G.S., Sukhanov D.S., Аyzikov D.L. Pobochnye deystviya protivotuberkuleznykh preparatov i metody ikh ustraneniya: ucheb. posobie. [Side effects of anti-tuberculosis drugs and their management techniques. Manual]. St. Petersburg, 2011, 88 p.
2. Vasilyeva I.A. et al. Tuberculosis chemotherapy: problems and perspectives. Vestn. Ros. Akad. Med. Nauk., 2012, no. 11. pp. 9-14. (In Russ.)
3. Vasilyeva I.A. et al. Postponed outcomes of using standard chemotherapy regimens in respiratory tuberculosis patients. Tuberculosis and Lung Diseases, 2012, no. 4. pp. 3-8. (In Russ.)
4. Galkin V.B. et al. State of TB care provision for the population of Northern-Western Federal District in 2007-2012. Med. Alyans, 2013, no. 3, pp. 5-24. (In Russ.)
5. Kildyusheva E.I. et al. How to improve the treatment results of destructive pulmonary tuberculosis with drug resistant mycobacteria? Tuberculosis and Lung Diseases, 2015, no. 5. pp. 77-78. (In Russ.)
6. Motus I.Ya. et al. Surgical treatment of pulmonary tuberculosis. Problems, outcomes, prospectives. Vestn. Uralskoy Med. Akadimicheskoy Nauki, 2009, no. 3 (26), pp. 103-106. (In Russ.)
7. Motus I.Ya. et al. Pulmonary tuberculosis surgery. Tuberculosis and Lung Diseases, 2012, no. 6. pp. 14-20. (In Russ.)
8. Ovchinnikova Yu.E., Starshinova А.А., Dovgalyuk I.F. Optimization of chemotherapy regimens in primary tuberculosis in children. Tuberculosis and Lung Diseases, 2009, no. 1. pp. 36-39. (In Russ.)
9. Skornyakov S.N. et al. Surgical treatment of destructive drug resistant pulmonary tuberculosis. Tuberculosis and Lung Diseases, 2015, no. 3. pp. 15-20. (In Russ.)
10. Starshinova А.А. et al. Evolution in TB control is the search for new methods and medications effective in tuberculosis treatment. Praktich. Meditsina, 2014, no. 7 (83), pp. 127-132. (In Russ.)
11. Ftiziatriya. Natsionalnye klinicheskie rekomendatsii. [Phthisiology. National clinical Recommendations]. Ed. by P.K. Yablonsky, Moscow, GEOTAR-Media Publ., 2016, 240 p.
12. Chernokhaeva I.V. et al. Monitoring of side effects during therapy of respiratory tuberculosis with multiple drug resistance when using thioureideiminomethyliiridine perchlorate (perchlozon). Med. Alyans, 2014, no. 2. pp. 59-65. (In Russ.)
13. Schegertsov D.Yu. et al. Impact of side effects of anti-tuberculosis drugs on the treatment outcomes in those with multiple drug resistant pulmonary tuberculosis treated by DOTS-PLUS regimens. Bull. Sibir. Meditsiny, 2011, no. 1. pp. 132-136. (In Russ.)
14. Yablonsky P.K. Russian tuberculosis control - the choice of the way for further development. Med. Alyans, 2013, no. 3. pp. 5-24. (In Russ.)
15. Chernokhaeva I. et al. Therapy of pulmonary tuberculosis with multidrug-resistant Mycobacterium tuberculosis using tioureidoiminomethylpyridinium perchlorate (Perсhlozon) (Epub.). IJTRA, 2015, vol. 3, issue 03, pp. 59-62. Available from: www.ijtra.com
16. Companion handbook to the WHO guidelines for the programmatic management of drug-resistant tuberculosis. World Health Organization; 2014. 448 p.
17. Cummings I. et al. Surgery and tuberculosis. Curr. Opin. Pulm. Med., 2012, vol. 18, no. 3, pp. 241-245.
18. Kempker R.R. et al. Surgical treatment of drug-resistant tuberculosis. Lancet Infect. Dis., 2012, vol. 12, no. 2, pp. 157-166.
19. Marrone M.T. et al. Surgical interventions for drug-resistant tuberculosis: a systematic review and meta-analysis. Int. J. Tuberc. Lung Disease, 2013, vol. 17, no. 1, pp. 6-16.
20. Vashakidze S. et al. Favorable outcomes for multidrug and extensively drug resistant tuberculosis patients undergoing surgery. Ann. Thorac. Surg., 2013, vol. 95, no. 6, pp. 1892-1898.
21. Yablonskiy P. et al. Surgical treatment of pulmonary tuberculosis. Complex Pleuropulmonary Infections: Eur. Respir. Monograph., 2013, vol. 61, ch. 3, pp. 20-36.
22. Yaldiz S. et al. Surgery offers high cure rates in multidrug-resistant tuberculosis. Ann. Thorac. Cardiovasc. Surg., 2011, vol. 17, no. 2, pp. 143-147.
Review
For citations:
Marfina G.Yu., Vladimirov K.B., Kudryashov G.G., Istomina E.V., Avetisyan A.O. CLINICAL CASE OF EFFECTIVE HOLISTIC TREATMENT OF BILATERIAL FIBROUS CAVERNOUS PULMONARY TUBERCULOSIS. Tuberculosis and Lung Diseases. 2017;95(3):62-68. (In Russ.) https://doi.org/10.21292/2075-1230-2017-95-3-62-68