Tuberculous recombinant allergen as a part of preventive examination for tuberculosis among patients of 24-hour social service institutions
https://doi.org/10.21292/2075-1230-2019-97-7-42-47
Abstract
The objective of the study: To assess the efficacy of comprehensive examination using the skin test with tuberculous recombinant allergen in standard dilution (TRA) and fluorography with the mobile X-ray unit in the patients living in social service institutions for a long period of time.
Subjects and methods: 624 persons living in social service institutions were examined, of them 438 walking patients had fluorography tests by the mobile X-ray unit and a skin test with TRA. 186 immobile and partially mobile patients had sputum microscopy and the skin test with TRA.
Results. It was found out that sputum microscopy for acid-fast mycobacteria was uninformative for early detection of tuberculosis in immobile and partially mobile patients of social service institutions and it should be used simultaneously with TRA test. Immunodiagnostics in the patients of these institutions allowed identifying risk groups facing high risk to develop active tuberculosis in 6.6% of cases and prescribing them with preventive treatment in a timely manner.About the Authors
A. A. Shurygin
E.A. Vagner Perm State Medical University; Perm Regional Ministry of Health
Russian Federation
Russian Federation
Aleksandr A. Shurygin - Doctor of Medical Sciences, Head of Phthisiology Department.
26, Petropavlovskaya St., Perm, 614990I. V. Perminovа
Perm Regional Clinical Phthisiopulmonology Medical Center
Russian Federation
Russian Federation
Iraida V. Perminova - Candidate of Medical Sciences, Head of Statistics Department.
160, Kosmonavtov Highway, Perm, 614990, Phone: +7 (342) 206-46-03
A. A. Kovtun
Perm Regional Clinical Phthisiopulmonology Medical Center
Russian Federation
Russian Federation
Anna A. Kovtun - Candidate of Medical Sciences, Radiodentist.
160, Kosmonavtov Highway, Perm, 614990, Phone: +7 (342) 206-46-03
V. P. Plotnikov
Perm Regional Clinical Phthisiopulmonology Medical Center
Russian Federation
Russian Federation
Vadim P. Plotnikov - Head Physician.
160, Kosmonavtov Highway, Perm, 614990, Phone: +7 (342) 206-46-03
E. G. Novikovа
Perm Regional Ministry of Health; Perm Regional Clinical Phthisiopulmonology Medical Center
Russian Federation
Russian Federation
Elena G. Novikova - Deputy Head Doctor for Medical Activities.
160, Kosmonavtov Highway, Perm, 614990, Phone: +7 (342) 206-46-03
D. A. Kudlаy
Immunology Research Institute by the Federal Medical Biological Agency
Russian Federation
Russian Federation
Dmitry A. Kudlay - Doctor of Medical Sciences, Leading Researcher of Laboratory of Personalized Medicine and Molecular Immunology no. 71.
24, Kashirskoye Highway, Moscow, 115522
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Review
For citations:
Shurygin A.A., Perminovа I.V., Kovtun A.A., Plotnikov V.P., Novikovа E.G., Kudlаy D.A. Tuberculous recombinant allergen as a part of preventive examination for tuberculosis among patients of 24-hour social service institutions. Tuberculosis and Lung Diseases. 2019;97(7):42-47. (In Russ.) https://doi.org/10.21292/2075-1230-2019-97-7-42-47
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